Brock Biology of Microorganisms (15th Edition)
Brock Biology of Microorganisms (15th Edition)
15th Edition
ISBN: 9780134261928
Author: Michael T. Madigan, Kelly S. Bender, Daniel H. Buckley, W. Matthew Sattley, David A. Stahl
Publisher: PEARSON
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Chapter 26.9, Problem 1CR

The complement system is composed of soluble proteins that catalyze bacterial opsonization and cell lysis. Complement is triggered by antibody interactions or by interactions with nonspecific activators, such as mannose-binding lectin. Complement activation may be a product of either innate or adaptive immunity. Complement may enhance phagocytosis, cause target cell lysis, or induce an inflammatory response.

Describe the complement system. Is the order of protein interactions important? Why or why not? Identify the components of the mannose-binding lectin pathway for complement activation. Identify the components of the alternative pathway for complement activation. How do these complement activation pathways differ from the classical pathway?

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Brock Biology of Microorganisms (15th Edition)

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