Chapter 26.3, Problem 7P

Interpretation Introduction

Interpretation:

How to prepare the aminoacid shown enantioselectively is to be outlined.

Concept introduction:

α-aminoacids can be prepared enantioselectively by hydrogenation of a suitable Z enamido acid with a chiral hydrogenation catalyst such as the coordination complexes of Rh(I) with 1,5-cyclooctadiene(COD) and a chiral diphosphine such as (R,R)-1,2-bis(o-anisylphenylphosphino)ethane (DiPAMP ligand).

To outline:

The preparation of the aminoacid shown enantioselectively.