The impaired activation of vitamin D and its consequences on calcium and phosphate homeostasis, parathyroid function, and mineralization of bone in persons with CKD. Introduction: Chronic kidney disease may be accompanied by various factors like Hyperphosphatemia, hypocalcemia, hyperparathyroidism, and many skeletal complications. The disorder of mineral and bone impairment begins early in CKD

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Chapter 26, Problem 3RE

A.

Summary Introduction

To determine: The impaired activation of vitamin D and its consequences on calcium and phosphate homeostasis, parathyroid function, and mineralization of bone in persons with CKD.

Introduction: Chronic kidney disease may be accompanied by various factors like Hyperphosphatemia, hypocalcemia, hyperparathyroidism, and many skeletal complications. The disorder of mineral and bone impairment begins early in CKD

B.

Summary Introduction

To explain: The possible complications of the administration of activated forms of vitamin D on parathyroid function and calcium and phosphate homeostasis.

Introduction: The CKD represents the abnormal functioning of the kidneys, which is due to the permanent loss of the nephrons. The person with CKD develops various impairments like hyperparathyroidism, serum calcium, and phosphorus levels. The increase in the calcium-phosphate product over 60-70 metastatic calcification is seen.

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