Bundle: Biology: The Unity and Diversity of Life, Loose-leaf Version, 14th + LMS Integrated for MindTap Biology, 2 terms (12 months) Printed Access Card
Bundle: Biology: The Unity and Diversity of Life, Loose-leaf Version, 14th + LMS Integrated for MindTap Biology, 2 terms (12 months) Printed Access Card
14th Edition
ISBN: 9781305775480
Author: Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher: Cengage Learning
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Chapter 26, Problem 2DAA

Neanderthal Hair Color The MCIR gene regulates pigmentation in humans (Sections 14.1 and 15.l revisited), .so loss-of-function mutations in this gene affect hair and .skin color. A person with two mutated alleles for this gene makes more of the reddish melanin than the brownish melanin, resulting in red hair and pa le skin. DNA extracted from two Neanderthal fossils contains a mutated MC1R allele that has not yet been found in humans, To see how the. Neanderthal mutation affects the function of the MC1R gene, Carles Lalueza-Fox and her team introduced the allele into cultured monkey cells (FIGURE 26.1 6).

Chapter 26, Problem 2DAA, Neanderthal Hair Color The MCIR gene regulates pigmentation in humans (Sections 14.1 and 15.l

FIGURE 26.16 MC1R activity in monkey cells transgenic for an unmutated MClR gene, the Neanderthal MC1R allele or the gene for green fluorescent protein (GFP). GFP is- not related to MC1R.

2. What does this imply about the mutation’s effect on Neanderthal hair color?

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY