Study Guide/solutions Manual For Organic Chemistry
Study Guide/solutions Manual For Organic Chemistry
6th Edition
ISBN: 9781260475678
Author: Janice Gorzynski Smith Dr.
Publisher: McGraw-Hill Education
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Chapter 25.5, Problem 23P

(a) What product is formed by the Claisen rearrangement of compound Z? (b) Using what you have learned about ring-closing metathesis in Chapter 26, draw the product formed when the product in part (a) is treated with Grubbs catalyst. These two reactions are key steps in the synthesis of garsubellin A, a biologically active natural product that stimulates the synthesis of the neurotransmitter acetylcholine. Compounds of this sort may prove to be useful drugs for the treatment of neurodegenerative diseases such as Alzheimer’s disease.

Chapter 25.5, Problem 23P, Problem 27.25
(a) What product is formed by the Claisen rearrangement of compound Z? (b) Using what

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