Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
16th Edition
ISBN: 9781260231700
Author: Sylvia S. Mader, Michael Windelspecht
Publisher: McGraw Hill Education
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Chapter 25.3, Problem 2CYP

Describe the movement of information from the nucleus to the formation of a functional protein.

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"One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE.  1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site  4. BMP4 on outside-> nodal  Are all of these occuring opposite to AVE?
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Inquiry Into Life (16th Edition)

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