Organic Chemistry Study Guide and Solutions
Organic Chemistry Study Guide and Solutions
6th Edition
ISBN: 9781936221868
Author: Marc Loudon, Jim Parise
Publisher: W. H. Freeman
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Chapter 25, Problem 25.10P
Interpretation Introduction

Interpretation:

A curved arrow mechanism for the reduction of mevaldehyde shown on page number 1294 (Equation 25.9b) is to be drawn.

Concept Introduction:

The hydride donor, NADH or NADPH, activates the carbonyl group of the amino acid by protonating the carbonyl carbon. This reduces the mevaldehyde to mevalonate by cleavage of the bond between nitrogen and hydrogen atoms.

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