EBK PRINCIPLES OF HUMAN PHYSIOLOGY
6th Edition
ISBN: 9780134399485
Author: STANFIELD
Publisher: PEARSON CO
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Chapter 2.5, Problem 1aCTQ
Summary Introduction
To determine:
The mechanism by which ricin induces death.
Introduction:
Ricin is found in the castor beans and if castor beans are chewed and swallowed, then they may cause injury due to their poisonous nature. It can also be obtained from the waste material left by the processing of castor beans. The grain sized dose of ricin is sufficient to kill the person.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 2 Solutions
EBK PRINCIPLES OF HUMAN PHYSIOLOGY
Ch. 2.1 - Prob. 2.1.1QCCh. 2.1 - Prob. 2.1.2QCCh. 2.1 - Prob. 2.1.3QCCh. 2.1 -
List the four types of chemical interactions...Ch. 2.2 - How does the impact Of Tay Sachs on the...Ch. 2.2 - In order to eradicate genetic diseases, such as...Ch. 2.2 - What would be the advantages and disadvantages of...Ch. 2.2 - Prob. 2.2.1QCCh. 2.2 - Prob. 2.2.2QCCh. 2.2 - Prob. 2.2.3QC
Ch. 2.2 - Prob. 2.2.4QCCh. 2.4 - Prob. 2.3.1QCCh. 2.4 - Describe the role of transmembrane proteins in the...Ch. 2.5 -
Why is only maternal mitochondrial DNA passed to...Ch. 2.5 -
How can mDNA. Be used to determine ancestry?
Ch. 2.5 - What are some diseases related to genetic...Ch. 2.5 -
Define transcription and translation. Where in...Ch. 2.5 -
Describe the functions of RNA polymerase in...Ch. 2.5 -
What is the name of the first of a polypeptide...Ch. 2.5 - Prob. 1aCTQCh. 2.5 - Why would preventing the larger ribosomal subunit...Ch. 2.5 - If ricin B induced exocytosis rather than...Ch. 2.6 -
Explain why and how a mutation in a...Ch. 2.6 -
Which characteristic(s) of cancer cells are...Ch. 2.6 - Prob. 3CTQCh. 2.6 - Prob. 2.5.1QCCh. 2.6 - Name the five stages of mitosis. During which...Ch. 2 - Prob. 1ECh. 2 - Prob. 2ECh. 2 -
Which of the following molecules is not a...Ch. 2 - Hydrogen bonding between the amino hydrogen of one...Ch. 2 -
Which of the following nucleic acids is not a...Ch. 2 - Prob. 6ECh. 2 - Prob. 7ECh. 2 - Prob. 8ECh. 2 - Prob. 9ECh. 2 - Prob. 10ECh. 2 - Prob. 11ECh. 2 - Prob. 12ECh. 2 - Prob. 13ECh. 2 -
During which phase of mitosis is the mitotic...Ch. 2 -
During which phase of mitosis do the chromosome...Ch. 2 -
Monosaccharides are (polar/nonpolar/amphipathic)...Ch. 2 - Triglycerides are (polar/nonpolar/amphipathic)...Ch. 2 - Prob. 18ECh. 2 - Prob. 19ECh. 2 - Prob. 20ECh. 2 - Prob. 21ECh. 2 - Prob. 22ECh. 2 - Prob. 23ECh. 2 - Prob. 24ECh. 2 - Prob. 25ECh. 2 - Prob. 26ECh. 2 -
The first section of a polypeptide to be...Ch. 2 -
Replication of DNA occurs during...Ch. 2 -
Division of the cytoplasm into two daughter...Ch. 2 - Prob. 30ECh. 2 - Prob. 31ECh. 2 - Prob. 32ECh. 2 -
Describe the structure of the plasma membrane....Ch. 2 - Prob. 34ECh. 2 - Prob. 35ECh. 2 - Prob. 36ECh. 2 - Prob. 37ECh. 2 - Prob. 38ECh. 2 -
Draw a flowchart showing the synthesis of...Ch. 2 -
Plasma, which is the fluid portion of blood, is...Ch. 2 -
Name some factors that cause cancer and potential...Ch. 2 - Prob. 42ECh. 2 - Prob. 43ECh. 2 - Prob. 44E
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