Understanding Pathophysiology, 6e
Understanding Pathophysiology, 6e
6th Edition
ISBN: 9780323354097
Author: Sue E. Huether RN PhD, Kathryn L. McCance RN PhD
Publisher: Elsevier Science
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Chapter 24.3, Problem 1QC
Summary Introduction

To explain: The way by which Laplace law functions in aneurysms.

Concept introduction: A localized, abnormal, weak spot on the blood vessel which causes an outward bulging is called aneurysm. It occurs due to weakened blood vessel wall. Aneurysm also occurs as a result of hereditary condition or an acquired disease. It is the initial stage of thrombosis and embolization.

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calculate the questions showing the solution including variables,unit and equations all the questiosn below using the data a) B1,   b) B2,   c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim   g) k10 h) k12 i) k21 j) initial concentration (C0)   k) central compartment volume (V1) l) steady-state volume (Vss)   m) clearance (CL)  AUC (0→10 min) using trapezoidal rule n)  AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞)   p) total AUC (using short cut method) q) volume from AUC (VAUC)
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