
To explain: The reason why the process of differentiation is essential to specialization with an example.
Introduction: Differentiation and specialization of cells occur during development of the organisms. Cellular differentiation occurs during development wherein the cells differentiate from one cell type to another with the aid of molecular cell signaling. The process of cellular specialization makes the cell become specialized for a particular function.

Explanation of Solution
The cell can specialize only if the cell differentiates. During development, the cells are first formed by rapid mitosis called as cleavage. During which the growth phases do not occur. The process of differentiation is reversible, provided the essential cell signaling factors are available, but the process of specialization is irreversible. Once the cell is specialized, its fate is fixed, and the cell will perform the respective set of functions until death. Cell specialization occurs as part of division of labor between cells. The cells are assigned a particular set of functions.
The embryonic cells first multiply rapidly to form several cells. The cells acquire new characteristics that cause several specific changes within the cell. This process is called as cellular differentiation. Only if differentiation occurs in immature cells, the cells can specialize. Thus, differentiation is the first and foremost process for specialization to occur. Therefore, the process of differentiation is essential for specialization to occur.
Example:
Specialization of red blood cells begins from the gastrula. The following are the steps involved in the specialization of cells to form the erythrocytes:
- 1. The blastula forms the gastrula.
- 2. The mesodermal cells of the gastrula differentiate to form the hematopoietic stem cells that are multipotent.
- 3. The hematopoietic stem cells differentiate into common myeloid progenitor cells that are also multipotent.
- 4. The common myeloid progenitor cell specializes into unipotent stem cells called as proerythroblasts.
- 5. The proerythroblast specializes into erythroblasts.
- 6. Erythroblast undergoes various changes and forms several intermediate cells; the nucleus is expelled and finally forms the reticulocyte.
- 7. The reticulocyte specializes into erythrocyte in the blood stream.
The cells that differentiate give rise to several cell lineages, but the cell that specialized can give rise to only one cell lineage.
As the cells must differentiate first in order for the cells to specialize, the process of differentiation is essential for specialization.
Want to see more full solutions like this?
- What is the concept "calories consumed must equal calories burned" in regrads to nutrition?arrow_forwardYou intend to insert patched dominant negative DNA into the left half of the neural tube of a chick. 1) Which side of the neural tube would you put the positive electrode to ensure that the DNA ends up on the left side? 2) What would be the internal (within the embryo) control for this experiment? 3) How can you be sure that the electroporation method itself is not impacting the embryo? 4) What would you do to ensure that the electroporation is working? How can you tell?arrow_forwardDescribe a method to document the diffusion path and gradient of Sonic Hedgehog through the chicken embryo. If modifying the protein, what is one thing you have to consider in regards to maintaining the protein’s function?arrow_forward
- The following table is from Kumar et. al. Highly Selective Dopamine D3 Receptor (DR) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J. Med Chem 2016.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. You are a chef in a fancy new science-themed restaurant. You have a recipe that calls for 1 teaspoon of resinferatoxin, but you feel uncomfortable serving foods with "toxins" in them. How much capsaicin could you substitute instead?arrow_forwardWhat protein is necessary for packaging acetylcholine into synaptic vesicles?arrow_forward
- 1. Match each vocabulary term to its best descriptor A. affinity B. efficacy C. inert D. mimic E. how drugs move through body F. how drugs bind Kd Bmax Agonist Antagonist Pharmacokinetics Pharmacodynamicsarrow_forward50 mg dose of a drug is given orally to a patient. The bioavailability of the drug is 0.2. What is the volume of distribution of the drug if the plasma concentration is 1 mg/L? Be sure to provide units.arrow_forwardDetermine Kd and Bmax from the following Scatchard plot. Make sure to include units.arrow_forward
- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education





