FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
11th Edition
ISBN: 2818440070938
Author: Martini
Publisher: PEARSON C
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Chapter 24, Problem 9RQ
Summary Introduction
Introduction:
The secretion of digestive enzymes and other substances in the digestive tract is a well regulated process. It requires specific stimuli that can trigger the release.
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Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions
SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q
a) B1,
b) B2,
c) hybrid rate constant (1)
d) hybrid rate constant (2)
e) t1/2,dist
f) t1/2,elim
g) k10
h) k12
i) k21
j) initial concentration (C0)
k) central compartment volume (V1)
l) steady-state volume (Vss)
m) clearance (CL) AUC (0→10 min) using trapezoidal rule
n) AUC (20→30 min) using trapezoidal rule
o) AUCtail (AUC360→∞)
p) total AUC (using short cut method)
q) volume from AUC (VAUC)
Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.
Chapter 24 Solutions
FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY
Ch. 24 - Prob. 1CPCh. 24 - Prob. 2CPCh. 24 - Prob. 3CPCh. 24 - Prob. 4CPCh. 24 - Name the layers of the gastrointestinal tract...Ch. 24 - Which is more efficient in propelling intestinal...Ch. 24 - Prob. 7CPCh. 24 - Prob. 8CPCh. 24 - Prob. 9CPCh. 24 - Prob. 10CP
Ch. 24 - Prob. 11CPCh. 24 - Prob. 12CPCh. 24 - Prob. 13CPCh. 24 - Name the structure connecting the pharynx to the...Ch. 24 - Prob. 15CPCh. 24 - Identify the muscles associated with the pharynx...Ch. 24 - What is occurring when the soft palate and larynx...Ch. 24 - Name the four major regions of the stomach.Ch. 24 - Prob. 19CPCh. 24 - Prob. 20CPCh. 24 - Prob. 21CPCh. 24 - The digestion of which nutrient would be most...Ch. 24 - Prob. 23CPCh. 24 - Prob. 24CPCh. 24 - Name the three regions of the small intestine from...Ch. 24 - Prob. 26CPCh. 24 - Prob. 27CPCh. 24 - How would the pH of the intestinal contents be...Ch. 24 - Prob. 29CPCh. 24 - Name some major histological differences between...Ch. 24 - Prob. 31CPCh. 24 - Prob. 32CPCh. 24 - Prob. 33CPCh. 24 - Prob. 34CPCh. 24 - Prob. 35CPCh. 24 - Prob. 36CPCh. 24 - Prob. 37CPCh. 24 - What body systems may be affected by inadequate...Ch. 24 - The enzymatic breakdown of large molecules into...Ch. 24 - Prob. 2RQCh. 24 - Prob. 3RQCh. 24 - Prob. 4RQCh. 24 - Prob. 5RQCh. 24 - Prob. 6RQCh. 24 - Prob. 7RQCh. 24 - Prob. 8RQCh. 24 - Prob. 9RQCh. 24 - Prob. 10RQCh. 24 - Prob. 11RQCh. 24 - Prob. 12RQCh. 24 - Prob. 13RQCh. 24 - Prob. 14RQCh. 24 - Prob. 15RQCh. 24 - What three basic mechanisms regulate the...Ch. 24 - Prob. 17RQCh. 24 - What are the primary digestive functions of the...Ch. 24 - Prob. 19RQCh. 24 - What are the three primary functions of the large...Ch. 24 - What two positive feedback loops are involved in...Ch. 24 - Prob. 22RQCh. 24 - Prob. 23RQCh. 24 - Prob. 24RQCh. 24 - Through which layers of a molar would an oral...Ch. 24 - Prob. 26RQCh. 24 - Prob. 27RQCh. 24 - Prob. 28RQCh. 24 - Some people with gallstones develop pancreatitis....Ch. 24 - Prob. 30RQCh. 24 - A condition known as lactose intolerance is...Ch. 24 - Prob. 32RQCh. 24 - Prob. 1CCCh. 24 - Prob. 2CC
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