Campbell Essential Biology with Physiology (5th Edition)
5th Edition
ISBN: 9780321967671
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece, Kelly A. Hogan
Publisher: PEARSON
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Chapter 24, Problem 8SQ
Summary Introduction
To determine: The type of cells missing in a baby born with an immunodeficiency disease who is not producing any antibodies.
Concept introduction:
An immunodeficiency is a disorder in which an immune system in response to antigen is defective or absent. Antibodies are produced in response to a certain antigen.
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A person with type A+ blood gets a transfusion
with type O- blood. What is most likely to happen
to the recipient?
A) The recipient's blood will agglutinate
(clump) due to the presence of natural
antibodies in the recipient's blood.
B) Nothing because the donor's blood is
compatible with the recipient's blood.
C) The recipient's blood will agglutinate
(clump) due to the presence of natural
antigens on the recipient's blood cells.
What is Natural antibodies?
Although we lumped all lymphocytes together (normal and unusually large ones), what is the correct name for the large (activated) B-lymphocytes that are producing antibodies?
Chapter 24 Solutions
Campbell Essential Biology with Physiology (5th Edition)
Ch. 24 - Prob. 1SQCh. 24 - Classify each of the following components of the...Ch. 24 - Prob. 3SQCh. 24 - What makes a secondary immune response faster than...Ch. 24 - Prob. 5SQCh. 24 - Prob. 6SQCh. 24 - Prob. 7SQCh. 24 - Prob. 8SQCh. 24 - Prob. 9SQCh. 24 - Once vaccinated, you have had a primary exposure...
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- What is the difference between an allergy and an autoimmune response?arrow_forwardIn adults, spleen and lymph nodes link the hematologic and immune systems as they are the sites for blood cell proliferation, differentiation and... A) Hematopoiesis B) Central tolerance C) Destruction/removal D) Diapedesisarrow_forwardYou have a patient who has been injured by a rusty nail. As a precaution, you vaccinate her against tetanus. In response to the vaccine, how does her body produce antibodies against C. tetani and prevent future illness due to tetanus? A)B cells that produce an appropriate antibody undergo genomic rearrangement in order to produce other cells that secrete the same antibody. B)Every cell in her immune system produces antibodies against C. tetani. C)B cells with an appropriate antibody are stimulated to divide, producing plasma cells that make antibodies to C. tetani, and memory cells that "remember" C. tetani. D)Every B cell in her body produces antibodies against C. tetani.arrow_forward
- Choose one: 1- what are the antigenic determinant in the variable region of antibodies? Allotypes or idyotypes or isotypes ---------------------------------choose one: 2-When an antibody binds to more than one antigenic particle the best description will be: Cross reacting or clonal expansion or proliferation ------------------------------------------ choose one: 3-Antigen dependent phase during B cell maturation occur Peripheral tissues or bone marrow or spleen only?arrow_forward____________ are suspensions of killed or live germs which is employed to induce the production of antibodies and bring forth immunity.a) Vaccines b) Medicines c) Antibiotics d) Antigensarrow_forwardWhat are ABO blood-group antigens?arrow_forward
- How are antibodies unique? Please discuss the structure of an antibody. What are the V and C regions? Discuss how the few hundred genes involved are capable of making endless amounts of antibodies. Besides medical treatment what is another way antibodies can be used?arrow_forwardWhich of the following is NOT a professional antigen presenting cell (i.e. doesn’t express MHCII)? A) neutrophil B) B cell C) dendritic cell D) macrophage E) all of the above are professional antigen presenting cellsarrow_forward(56) A 1 year old boy dies of staphylococcal pneumonia. He has had multiple skin infections since birth. Separation of the umbilical cord was delayed. A skin window test was performed and no leukocyte accumulated on the cover ship. The cytometric analysis showed that only 5% of the T lymphocytes reacted with a monoclonal antibody to leukocyte functional antigen-1 chain (CD 18) compared with reactivity of 62 % for a normal subject. Just prior to death, his leukocyte count was 75,000/mm3. Which of the following is the most likely diagnosis? (A) AIDS (B) Cogenital Asplenia (C)Leukocyte Adhesion Deficiency (D) Severe Combined Immunodeficiency Disease (E) X linked agammaglobulinemiaarrow_forward
- A 40-year-old man with a complement deficiency agrees to participate in a clinical study of immune mechanisms. The subject is unable to activate the complement system by the classical pathway, but he can activate the complement system by the alternate pathway. Deletion of which of the following components is consistent with these findings? A) C2 B) C3 C) C5 D) C8 E) Factor B F) Factor D OG) Factor H OH) von Willebrand factorarrow_forwardEven though instances of fetal, maternal ABO, incompatibility are common, severe hemolytic disease due to ABO incompatibility is rare. Which of the following best explains this difference? A) ABO incompatibility causes extensive extra medullary hematopoiesis B) antibodies against ABO antigens do not bind complement C) the maternal immune system is tolerant to ABO ANTIGENS D) most anti- A or anti- B antibodies are of IgM type and do not cross the placenta E) the presence of concurrent Rh incompatibility decreases the immunogenicity of erythrocytesarrow_forward. A) What is the significance of producing monoclonal antibodies? B) What is the role of cell culture in production of monoclonal antibodies? C) Name and briefly explain the use of any 4 commercially available monoclonal antibodies.arrow_forward
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