Stoichiometry of the stearoyl-CoA desaturase should be convinced correct. Concept Introduction: In eukaryotes, addition of double bond to fatty acids does not occur until the fatty acid chain occupied its full length. But the dehydrogenation of stearoyl-CoA occurs in the middle of the chain Stearoyl-CoA + NADH + H + + O 2 → Oleoyl-CoA + 2 H 2 O Above reaction is catalyzed by stearoyl-CoA desaturase enzyme. This enzyme has a nonheme iron center. NADH and O 2 is required to run this reaction. As well as, two other proteins cytochrome b 5 reductase and cytochrome b 5 are needed. These three proteins are incorporated with ER membrane.

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Chapter 24, Problem 5P

Interpretation Introduction

Interpretation:

Stoichiometry of the stearoyl-CoA desaturase should be convinced correct.

Concept Introduction:

In eukaryotes, addition of double bond to fatty acids does not occur until the fatty acid chain occupied its full length. But the dehydrogenation of stearoyl-CoA occurs in the middle of the chain

Stearoyl-CoA + NADH + H+ + O2→ Oleoyl-CoA + 2 H2O

Above reaction is catalyzed by stearoyl-CoA desaturase enzyme. This enzyme has a nonheme iron center. NADH and O₂ is required to run this reaction. As well as, two other proteins cytochrome b₅ reductase and cytochrome b₅ are needed. These three proteins are incorporated with ER membrane.

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