Chapter 24, Problem 2Q

Interpretation Introduction

Interpretation:

The structure of hexapeptide using abbreviations on the basis of given reaction chains and products is be determined.

Concept introduction:

Peptides are formed by joining amino acids; amino acid residues are held by the amide linkages called peptide bonds. Peptides containing six amino acid residues are hexapeptides. Nucleophilic aromatic substitution reaction of amino acid with 2,4-dinitrofluorobenzene in mildly basic solution and subsequent hydrolysis of the polypeptide results in the formation of a particular mixture that contains amino acids in which theN-terminal amino acid is labeled with a 2,4-dinitrophenyl group.