HOLES HUMAN ANAT&PHYS (LL)
HOLES HUMAN ANAT&PHYS (LL)
15th Edition
ISBN: 9781264116577
Author: SHIER
Publisher: MCG
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Chapter 24, Problem 20CA
Summary Introduction

To define:

The genomic imprinting

Introduction:

The expression of the genes is influenced by many factors such as the genetic factors, environmental factors, and the epigenetic factors. The epigenetics refers to the changes occurring in the genome, which are not the resultant of the modification of the genome. The epigenetic changes alter the expression and activity of the gene and are above the level of genetics. Genomic imprinting is one of the epigenetic mechanisms.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY