Microbiology: An Introduction (13th Edition)
Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 24, Problem 1CAE

In August, a 24-year-old man from Virginia developed difficulty breathing and bilateral lobe infiltrates 2 months after driving through California. During initial evaluation, typical pneumonia was suspected, and he was treated with antibiotics. Efforts to diagnose the pneumonia were unsuccessful. In October, a laryngeal mass was detected, and laryngeal cancer was suspected; treatment with steroids and bronchodilators did not result in improvement. Lung biopsy and laryngoscopy detected diffuse granular tissue. He was treated with amphotericin B and discharged after 5 days. What was the disease? What might have been done differently to decrease the patient’s recovery time from 3 months to 1 week?

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A 45-year-old man complains of swelling of the neck and difficulty of breathing of 10-day duration. He has noticed some nasal stuffiness with hoarseness of his voice for about 3 weeks and had attributed these symptoms to an upper respiratory infection. He denies the use of alcohol but has smoked two packs of cigarettes per day for 32 years. Lately, he feels as though something is pushing against his throat. On physical examination, the patient’s face appears ruddy and swollen. The jugular veins are distended. What is the most likely diagnosis?What is the most likely cause?What are the anatomical structures involved?
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