The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations. Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

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Answer 1

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Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?

Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Answer 2

Question

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

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Answer 3

Question

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

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Answer 4

Question

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

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Answer 5

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

Answer 6

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Answer 7

Chapter 24, Problem 14PDQ

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered as the gain-of-function mutations.

Introduction: Cancer is caused when one of the alleles of an oncogene is mutated or both the alleles of tumor suppressor genes are mutated. The mutation in both genes affects the expression of these genes, which affects the regulation of the cell cycle.

Answer 8

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

Answer 9

Summary Introduction

To determine: The group out of tumor-suppressor genes and oncogenes in which mutations can be considered the loss-of-function mutations.

Introduction: When the genes of somatic cells are mutated, they are not passed to the next generation. Therefore, cancer is not inherited. When a mutation occurs in germ cells, then it makes cancer, inherited.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 24 - Prob. 1NST Ch. 24 - People with a genetic condition known as...Ch. 24 - Prob. 3NST Ch. 24 - Cancer can arise spontaneously, but it can also be...Ch. 24 - Prob. 1CS Ch. 24 - Prob. 2CS Ch. 24 - If you agree to participate and then learn that...Ch. 24 - HOW DO WE KNOW? In this chapter, we focused on...Ch. 24 - Prob. 2PDQ Ch. 24 - Where are the major regulatory points in the cell...

Solution Summary: The author explains that tumor-suppressor genes and oncogenes can be considered gain-of-function mutations.

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