Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
Genetics: A Conceptual Approach 6E w/ SaplingPlus (Six-Month Access)
6th Edition
ISBN: 9781319125929
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
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Chapter 23.3, Problem 30AQP
Summary Introduction

To explain:

The working of drugs that demethylate DNA.

Introduction:

The alteration to the structure of chromatin affects the gene expression which is known as epigenetic changes. These changes are considered to be the major reason behind cancer. The change in the structure of the protein which is related to transcription is DNA methylation. The methylation of base cytosine resulting in 5-methylcytosine that causes repression of transcription.

Summary Introduction

To determine:

Whether cancer-causing gene that responded to demethylation are likely to have been oncogenes or tumor-suppressor genes.

Introduction:

The disorder of cellular growth that occurs when the cell divides uncontrollably is known as cancer. Reason for cancer differs widely but most of the cancers result from the accumulation of mutations that leads to loss of control over the cell division process.

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