EP PRINCIPLES OF HUM.PHYS.-MOD.MAST.A+P
EP PRINCIPLES OF HUM.PHYS.-MOD.MAST.A+P
6th Edition
ISBN: 9780134407166
Author: STANFIELD
Publisher: PEARSON CO
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Chapter 23.3, Problem 2CTQ
Summary Introduction

To write:

The factors that enhance the likelihood for an individual to develop shingles.

Introduction:

Shingles refer to a viral infection, which leads to a painful rash. Though the condition can develop anywhere on the body, it most usually develops as a single stripe of blisters, which surrounds on either the right or left side of the torso. It is caused by a similar virus that causes chickenpox, that is, varicella-zoster virus.

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You aim to test the hypothesis that the Tbx4 and Tbx5 genes inhibit each other's expression during limb development. With access to chicken embryos and viruses capable of overexpressing Tbx4 and Tbx5, describe an experiment to investigate whether these genes suppress each other's expression in the limb buds. What results would you expect if they do repress each other? What results would you expect if they do not repress each other?
You decide to delete Fgf4 and Fgf8 specifically in the limb bud. Explain why you would not knock out these genes in the entire embryo instead.
You implant an FGF10-coated bead into the anterior flank of a chicken embryo, directly below the level of the wing bud. What is the phenotype of the resulting ectopic limb?  Briefly describe the expected expression domains of 1) Shh, 2) Tbx4, and 3) Tbx5 in the resulting ectopic limb bud.

Chapter 23 Solutions

EP PRINCIPLES OF HUM.PHYS.-MOD.MAST.A+P

Ch. 23.3 - Prob. 3CTQCh. 23.3 - Prob. 23.4.1QCCh. 23.3 - Prob. 23.4.2QCCh. 23.3 - Prob. 23.4.3QCCh. 23.3 - Prob. 23.4.4QCCh. 23.4 - Prob. 23.5.1QCCh. 23.4 - Prob. 23.5.2QCCh. 23.4 - Prob. 23.5.3QCCh. 23.5 - Prob. 23.6.1QCCh. 23.5 - Prob. 23.6.2QCCh. 23.5 - Prob. 23.6.3QCCh. 23.5 - Prob. 23.6.4QCCh. 23.6 - Prob. 1CTQCh. 23.6 - Prob. 2CTQCh. 23.6 - Prob. 3CTQCh. 23.6 - Prob. 23.7.1QCCh. 23.6 - Prob. 23.7.2QCCh. 23.6 - Prob. 1aCTQCh. 23.6 - Prob. 2aCTQCh. 23.6 - Prob. 3aCTQCh. 23.6 - Which class of antibody is induced in allergies...Ch. 23.6 - Does rheumatoid arthritis result from a humoral...Ch. 23.6 - Name two lymphoid organs that are innervated by...Ch. 23.6 - Prob. 1bCTQCh. 23.6 - Prob. 2bCTQCh. 23.6 - Prob. 3bCTQCh. 23 - Prob. 1ECh. 23 - Prob. 2ECh. 23 - Prob. 3ECh. 23 - Lymphocytes contact foreign antigen in all of the...Ch. 23 - Which of the following is not true about humoral...Ch. 23 - Macrophages a. are derived from monocytes. b....Ch. 23 - Activated cytotoxic T cells release pore-forming...Ch. 23 - Prob. 8ECh. 23 - Prob. 9ECh. 23 - Foreign antigens phagocytosed by macrophages are...Ch. 23 - Of the following events, which occurs earliest in...Ch. 23 - Prob. 12ECh. 23 - Prob. 13ECh. 23 - Prob. 14ECh. 23 - Prob. 15ECh. 23 - Fill in the blank with the abbreviation for the...Ch. 23 - Fill in the blank with the letter that applies to...Ch. 23 - A person who experiences life-threatening allergic...Ch. 23 - Prob. 19ECh. 23 - Prob. 20ECh. 23 - Prob. 21ECh. 23 - Prob. 22ECh. 23 - Prob. 23ECh. 23 - Prob. 24ECh. 23 - Prob. 25ECh. 23 - Immune responses exhibit four features, all of...Ch. 23 - Prob. 27ECh. 23 - Prob. 28ECh. 23 - Prob. 29ECh. 23 - Prob. 30E
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