LIFE: THE SCIENCE OF BIOLOGY
LIFE: THE SCIENCE OF BIOLOGY
11th Edition
ISBN: 9781319145125
Author: Sadava
Publisher: MAC HIGHER
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Chapter 23.2, Problem 4R
Summary Introduction

To review:

The differences between the two hypotheses for the wide range of genome sizes among organisms.

Introduction:

The size of genome in different organisms from bacteria to humans is very different. The genome of the bacteria Mycoplasma has about 470 genes, while the genome of humans has almost 21,000 genes. There is some sort of correlation between the organismal complexity and the genome size, but this is not a direct correlation.

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Draw a rough sketch of the control and experimental data using a normal dose/response curve plot: i.e. % of total bound ligand vs. concentration. Indicate Kd and Bmax on this sketch. You don’t need to use exact numbers, but the relative proportions should be close
Name something that could be happening to glutamate transporters that could have this effect on glutamate transport (i.e. the difference in glutamate transporters between control and experimental conditions). (Bonus: if you can also guess what the experimental condition is).
a. For the control condition, calculate Kd. Include units and show your work. b. For the control condition, calculate Bmax. Include units and show your work.  c. For the experimental condition, calculate Kd. Include units and show your work. For the experimental condition, calculate Bmax. Include units and show your work.
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