Calculate the average per-site, per-generation, nonsynonymous substitution rate between D. ananassae and the other three species. Also, give inputs about the type of selection of operating on the nonsynonymous sites based on the difference between the rate calculated in this part and question 1. Given: In the given study, a hypothetical gene encodes for the transcription factors in various species of Drosophila. According to the diagram given below, one exon of this gene is sequenced in four species. The matrix shows the number of synonymous and nonsynonymous substitutions between pairs of species of Drosophila, which evolved as a result of evolution. There are 2000 nonsynonymous and 600 synonymous substitutions sites of the exon. Introduction: The mutation rate is the rate used to calculate the frequency of new mutation in a single gene or one single organism, which have evolved over the time. The substitution rate is the rate which checks the DNA (deoxyribonucleic acid) sequence as the number of nucleotide substitute per site per unit of time.

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Chapter 23, Problem 4Q

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Calculate the average per-site, per-generation, nonsynonymous substitution rate between D. ananassae and the other three species. Also, give inputs about the type of selection of operating on the nonsynonymous sites based on the difference between the rate calculated in this part and question 1.

Given:

In the given study, a hypothetical gene encodes for the transcription factors in various species of Drosophila. According to the diagram given below, one exon of this gene is sequenced in four species.

The matrix shows the number of synonymous and nonsynonymous substitutions between pairs of species of Drosophila, which evolved as a result of evolution. There are 2000 nonsynonymous and 600 synonymous substitutions sites of the exon.

Introduction:

The mutation rate is the rate used to calculate the frequency of new mutation in a single gene or one single organism, which have evolved over the time. The substitution rate is the rate which checks the DNA (deoxyribonucleic acid) sequence as the number of nucleotide substitute per site per unit of time.

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