Chapter 23, Problem 3O

Summary Introduction

To discuss:

The mechanism of action, indication, cautions, contraindication, adverse effects, drug interaction, dosage and route of administration of antianginal drugs.

Concept introduction:

The heart is the unique organ that pumps oxygenated and receives deoxygenated blood from other organs. There are various malfunctions occur that damage the heart like low oxygen level causes angina pectoris, damage of heart cells leads to ischemia later to ischemic heart disease, deposits of fatty materials in the artery leads to Coronary Heart Disease (CAD), acute CAD leads to heart attack. The angina pectoris is classified into three classical types of chest pain they are chronic stable angina, unstable angina, and vasospastic angina. The nitrates and nitrites, Calcium Channel Blockers (CCBs), and the beta blockers are the classical three classes of drug that used as antianginal drugs.