Life: The Science of Biology
Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 23, Problem 1Q
Summary Introduction

To review:

The relationship between the number of synonymous substitutions and the years of divergence between each pair of species, with the help of a graph. Also, estimate the rates of synonymous substitutions per million years and per generation for the complete axon on a per-site basis.

Given:

In the given study, a hypothetical gene encodes for the transcription factor in various species of Drosophila. According to the diagram (Figure 1) given below, one exon of this gene is sequenced in four species.

Life: The Science of Biology, Chapter 23, Problem 1Q , additional homework tip  1

Figure 1: Million of years ago.

The matrix shows the number of synonymous and nonsynonymous substitutions between pairs of different Drosophila species, which evolved as a result of evolution. There are 2,000 nonsynonymous and 600 synonymous substitutions sites of the exon (Figure 2).

Figure 2: Matrix showing the number of synonymous and nonsynonymous substitutions between pairs of species of Drosophila.

Life: The Science of Biology, Chapter 23, Problem 1Q , additional homework tip  2

Introduction:

Biologists are able to make inference about the type of natural selection, by the study based on molecular evolutionary patterns of genes. These inferences are important to know, about the gene functioning and how they evolve over the time, in response to the new function and conditions.

Expert Solution & Answer
Check Mark

Explanation of Solution

According to the given analysis, there are, on an average, 54 synonymous substitutions occurs between the lineages. These lineages were diverged 18 million years ago. So, there are about 1.5 synonymous substitutions per million year for the entire exon.

Therefore, the information used for calculation of the rate is:

Time period: 18 million years ago

Substitution per million years: 1.5

Lineages: 2

Generation per year: 5

Synonymous sites: 600

Thus, for rate of substitution per generation is:

90,000,000 years × 2 lineages × 5 generations/year × 0.0000003 synonymous substitutions/generation = 3×10-7

Similarly, the rate of substitution per site is:

(90,000,000 years × 2 lineages × 5 generations/year × 0.0000003 synonymous substitutions/generation)/600 synonymous site = 5 × 10−10

Graph given below shows number of substitution along with millions of years.

Life: The Science of Biology, Chapter 23, Problem 1Q , additional homework tip  3

Conclusion

Therefore, it can be concluded that the rates are 3 ×10−7 per generations and 5 × 10−10 per site.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Students have asked these similar questions
Humans consider themselves amazingly clever and innovative, constantly developing "new" ways of altering the world around us. As material consumption has increased, many have turned to the ideas of recycling and reuse as a means to minimize some negative aspects of our modern consumerism. Mother Nature though is the ultimate innovator and, more importantly, the ultimate recycler.
H gene assorts independently from the I gene. Both on autosomes. One man and one woman, both of HhIAIB genotype. Determine the blood type of progeny and fractions out of 16
Alleles at the P locus control seed color. Plants which are pp have white seeds, white flowers and no pigment in vegetative parts. Plants which are P_ have black seeds, purple flowers and may have varying degrees of pigment on stems and leaves. Seed color can be assessed, visually, based on if the seed is white or not white A gene for mold resistance has been reported and we want to determine its inheritance and whether it is linked to P. For the purposes of this exercise, we will assume that resistance is controlled by a single locus M, and M_ plants are resistant and mm plants are susceptible.  Resistance can be measured, under greenhouse conditions, 2 weeks after planting, by injecting each seedling with a spore suspension. After two weeks, the seedlings can be rated as resistant or susceptible, based on whether or not tissue is actively sporulating. For this exercise we will use seed and data from the F10 generation of a recombinant inbred population produced using single seed…
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Text book image
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Text book image
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Text book image
Biology: The Unity and Diversity of Life (MindTap...
Biology
ISBN:9781337408332
Author:Cecie Starr, Ralph Taggart, Christine Evers, Lisa Starr
Publisher:Cengage Learning
Text book image
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Mechanisms of Genetic Change or Evolution; Author: Scientist Cindy;https://www.youtube.com/watch?v=5FE8WvGzS4Q;License: Standard Youtube License