CAMPBELL BIOLOGY:CONCEPTS+CONNECTIONS
CAMPBELL BIOLOGY:CONCEPTS+CONNECTIONS
10th Edition
ISBN: 9780136538875
Author: Taylor
Publisher: INTER PEAR
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Chapter 23, Problem 16TYK

SCIENTIFIC THINKING The studies described in Module 23.6 were funded by both government agencies and major pharmaceutical and medical supply companies. NIH grants for research on heart disease total more than $1.2 billion per year. Gather more information and form an opinion on how heart disease research should be funded, whether by private enterprises such as pharmaceutical companies, donor-supported nonprofit organizations, or government agencies. Write an essay arguing your point of view.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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