BSC 1005 PKG-W/MOD. MAST. ACCESS >CI<
17th Edition
ISBN: 9781269683364
Author: Reece
Publisher: Pearson Custom Publishing
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Chapter 23, Problem 12TYK
Summary Introduction
To analyze:
The blood sample is spun in the centrifuge. The components of the centrifuge are to be analyzed. The analysis shows the presence of straw-colored fluid at the top of the tube and the presence of dense red portion at the bottom.
Introduction:
The blood has components like white blood cells, red blood cells, immunoglobulins, ions, calcium, potassium, sodium, glucose, amino acids, hormones, platelets, and plasma proteins like fibrinogen.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Chapter 23 Solutions
BSC 1005 PKG-W/MOD. MAST. ACCESS >CI<
Ch. 23 - Connecting the Concepts 1. Use the following...Ch. 23 - Prob. 2TYKCh. 23 - When the doctor listened to Janets heart, he heard...Ch. 23 - Prob. 4TYKCh. 23 - Prob. 5TYKCh. 23 - Prob. 6TYKCh. 23 - Blood flows more slowly in the arterioles than in...Ch. 23 - Which of the following is not a true statement...Ch. 23 - Prob. 9TYKCh. 23 - Trace the path of blood starting in a pulmonary...
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