(a)
Interpretation: The structures of an
Concept Introduction:
When sodium cyanide is allowed to react with alkyl halide, halide group is replaced by cyanide group via SN2 nucleophilic substitution reaction. The cyanide group on treatment with lithium aluminum hydride which is a strong reducing agent, it reduces the cyanide group into methylene primary amine. There is a single carbon skeleton increment in the given compound through this process.
To find: Draw the structure of an alkyl halide that serve as a precursor in the preparation of the given amine (a)
Do the SN2 nucleophilic substitution reaction
(b)
Interpretation: The structures of an alkyl halide or carboxylic acid that serve as a precursor in the preparation of the given amines have to be drawn
Concept Introduction:
When sodium cyanide is allowed to react with alkyl halide, halide group is replaced by cyanide group via SN2 nucleophilic substitution reaction. The cyanide group on treatment with lithium aluminum hydride which is a strong reducing agent, it reduces the cyanide group into methylene primary amine. There is a single carbon skeleton increment in the given compound through this process.
To find: Draw the structure of an alkyl halide that serve as a precursor in the preparation of the given amine (b)
Do the SN2 nucleophilic substitution reaction
(c)
Interpretation: The structures of an alkyl halide or carboxylic acid that serve as a precursor in the preparation of the given amines have to be drawn
Concept Introduction:
When sodium cyanide is allowed to react with alkyl halide, halide group is replaced by cyanide group via SN2 nucleophilic substitution reaction. The cyanide group on treatment with lithium aluminum hydride which is a strong reducing agent, it reduces the cyanide group into methylene primary amine. There is a single carbon skeleton increment in the given compound through this process.
To find: Draw the structure of an alkyl halide that serve as a precursor in the preparation of the given amine (c)
Do the SN2 nucleophilic substitution reaction
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Chapter 22 Solutions
ORGANIC CHEMISTRY (LL) >CUSTOM PACKAGE<
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- Rank the compounds in each group below according to their reactivity toward electrophilic aromatic substitution (most reactive = 1; least reactive = 3). Place the number corresponding to the compounds' relative reactivity in the blank below the compound. a. CH₂F CH3 F b. At what position, and on what ring, is bromination of phenyl benzoate expected to occur? Explain your answer. :0: C-O phenyl benzoate 6.Consider the reaction below to answer the following questions. A B C NO₂ FeBr3 + Br₂ D a. The nucleophile in the reaction is: BODADES b. The Lewis acid catalyst in the reaction is: C. This reaction proceeds d. Draw the structure of product D. (faster or slower) than benzene.arrow_forwardPart 2. A solution of 6.00g of substance B in 100.0mL of aqueous solution is in equilibrium, at room temperature, wl a solution of B in diethyl ether (ethoxyethane) containing 25.0 g of B in 50.0 mL 9) what is the distribution coefficient of substance B b) what is the mass of B extracted by shaking 200 ml of an aqueous solution containing 10g of B with call at room temp): i) 100 mL of diethyl ether ii) 50ml of diethyl ether twice iii) 25ml of diethyl ether four timesarrow_forward- Rank the following groups of compounds from most acidic (1) to least acidic (4). Place the number corresponding to the compound's relative rank in the blank below the structure. a. NO₂ NO₂ CH2CH2CH2CH2OH CH3 CH3CH2CHOH CH3CH2CH2CH2OH NO₂ CH3CHCH2CH2OH b. OH OH CH₂OH CO₂H HC CN CN CNarrow_forward
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