Organic Chemistry (8th Edition)
8th Edition
ISBN: 9780134042282
Author: Paula Yurkanis Bruice
Publisher: PEARSON
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Textbook Question
Chapter 22.2, Problem 2P
Compare each of the mechanisms listed here with the mechanism for each of the two parts of the acid-catalyzed hydrolysis of an ester, indicating
a. similarities.
b. differences.
- 1. acid-catalyzed formation of a hydrate (Section 16.9)
- 2. acid-catalyzed conversion of an
aldehyde to a hemiacetal (Section 16.9) - 3. acid-catalyzed conversion of a hemiacetal to an acetal (Section 16.9)
- 4. acid-catalyzed hydrolysis of an amide (Section 15.12)
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Students have asked these similar questions
What is the major difference between the base-catalyzed and acid-catalyzed processes for nucleophilic addition of water to aldehydes and ketones?
a. The base-catalyzed reaction takes place rapidly because hydroxide ion is a much better nucleophile than neutral water.
b. The rate of reaction in base catalyzed process is slower than acid catalyzed process.
c. The acid-catalyzed reaction takes place rapidly because the protonated carbonyl compound is a much better electrophile than the neutral compound.
d. Only 1 and 3 are correct.
Select all the following statements that are correct.
A. The Tollens' test can be used to detect the presence of ketones.
B. A positive Schiff test results in the formation of a magenta coloured product.
C. A positive lodoform test results in the formation of a white precipitate.
D. A positive Tollens' test results in the formation of a silver mirror.
E. A positive lodoform test results in the formation of a bright yellow precipitate.
CORON
a. What reagent(s) are needed to synthesize the enamine below. Also, draw the resonance structure(s)
for the enamine.
b. Predict the product of the reaction between the enamine from part a and ethyl iodide. Also explain why
it forms, including any selectivities. Hint: Consider the type of reaction alkyl halides take part in and the
resonance structure(s) in part a.
Etl
Chapter 22 Solutions
Organic Chemistry (8th Edition)
Ch. 22.2 - Compare each of the mechanisms listed here with...Ch. 22.2 - Prob. 3PCh. 22.2 - Prob. 4PCh. 22.3 - a. Draw the mechanism for the following reaction...Ch. 22.5 - Prob. 7PCh. 22.5 - Propose a mechanism for the Co2+ catalyzed...Ch. 22.6 - Prob. 9PCh. 22.7 - Prob. 10PCh. 22.7 - Prob. 12PCh. 22.7 - Prob. 13P
Ch. 22.9 - Which of the following amino acid side chains can...Ch. 22.9 - Which of the following C-terminal peptide bonds is...Ch. 22.9 - Carboxypeptidase A has esterase activity as well...Ch. 22.10 - Arginine and lysine side chains fit into trypsins...Ch. 22.10 - Explain why serine proteases do not catalyze...Ch. 22.11 - If H2 18O is used in the hydrolysis reaction...Ch. 22.11 - Draw the pH-activity profile for an enzyme that...Ch. 22.12 - The pHactivity profile for glucose-6-phosphate...Ch. 22.12 - Prob. 23PCh. 22.13 - Draw the mechanism for the hydroxide ion-catalyzed...Ch. 22.13 - What advantage does the enzyme gain by forming an...Ch. 22.13 - Prob. 26PCh. 22.13 - Prob. 27PCh. 22.13 - Aldolase shows no activity if it is incubated with...Ch. 22 - Which of the following parameters would be...Ch. 22 - Prob. 29PCh. 22 - Prob. 30PCh. 22 - Prob. 31PCh. 22 - Indicate the type of catalysis that is occurring...Ch. 22 - The deuterium kinetic isotope effect (KH2O/KD2O)...Ch. 22 - Prob. 34PCh. 22 - Co2+ catalyzes the hydrolysis of the lactam shown...Ch. 22 - there are two kinds of aldolases. Class I...Ch. 22 - Prob. 37PCh. 22 - The hydrolysis of the ester shown here is...Ch. 22 - Prob. 39PCh. 22 - At pH = 12, the rate of hydrolysis of ester A is...Ch. 22 - 2-Acetoxycyclohexyl tosylate reacts with acetate...Ch. 22 - Proof that an imine was formed between aldolase...Ch. 22 - Prob. 43PCh. 22 - a. Explain why the alkyl halide shown here reacts...Ch. 22 - Triosephosphate isomerase (TIM) catalyzes the...
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