The major product of the given crossed Claisen condensation has to be stated. Concept introduction: In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

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Answer 1

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

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For each reaction below, decide if the first stable organic product that forms in solution will create a new CC bond, and check the appropriate box. Next, for each reaction to which you answered "Yes" to in the table, draw this product in the drawing area below. Note for advanced students: for this problem, don't worry if you think this product will continue to react under the current conditions - just focus on the first stable product you expect to form in solution. ? NH2 MgBr Will the first product that forms in this reaction create a new CC bond? ○ Yes ○ No MgBr ? Will the first product that forms in this reaction create a new CC bond? O Yes O No Click and drag to start drawing a structure. :☐ G x c olo Ar HE

Predicting As the lead product manager at OrganometALEKS Industries, you are trying to decide if the following reaction will make a molecule with a new C - C bond as its major product: H₂N O H 1. ? 2. H3O+ If this reaction will work, draw the major organic product or products you would expect in the drawing area below. If there's more than one major product, you can draw them in any arrangement you like. Be sure you use wedge and dash bonds if necessary, for example to distinguish between major products with different stereochemistry. 0 If the major products of this reaction won't have a new CC bond, just check the box under the drawing area and leave it blank. فا Explanation Check Click and drag to start drawing a structure.

Highlight the chirality (or stereogenic) center(s) in the given compound. A compound may have one or more stereogenic centers. OH OH OH OH OH OH

Answer 2

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

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Answer 3

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

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Answer 4

Question

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

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Answer 5

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 6

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 7

Chapter 22.14, Problem 22.44P

(a)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation has to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 8

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 9

(b)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 10

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 11

(c)

Interpretation Introduction

Interpretation:

The major product of the given crossed Claisen condensation is to be stated.

Concept introduction:

In crossed claisen condensation, the enolisable ester is deprotonated by alkoxide ion. This enolate ion undergoes a nucleophilic acyl substitution with non-enolisable ester to give a beta-keto ester. It is deprotonated by an alkoxide ion followed by protonation to give beta-keto ester. In this reaction, the electrophilic component is ester without alpha hydrogens.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 22.2A - Prob. 22.2P Ch. 22.4 - Without looking back, propose a mechanism for the...Ch. 22.4 - Prob. 22.8P Ch. 22.4 - Prob. 22.9P Ch. 22.5A - Prob. 22.10P Ch. 22.5A - Prob. 22.11P Ch. 22.5B - Prob. 22.12P Ch. 22.5B - Predict the products of the following reactions....Ch. 22.5B - Which compounds will give positive iodoform tests?...Ch. 22.5C - Propose a mechanism for the acid-catalyzed...

Solution Summary: The author explains that the major product of the given crossed Claisen condensation is shown below.

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