
(a)
Interpretation:
The side reaction that would occur in the condensation of ethyl acetate with sodium methoxide base is to be predicted.
Concept introduction:
In the claisen-ester condensation, nucleophilic acyl substitution takes place on an ester. The enolate ion acts as a nucleophile. It attacks the carbonyl carbon to form a tetrahedral intermediate. Acidity of beta-keto ester products is higher than simple
(b)
Interpretation:
The side reaction that would occur in the condensation of ethyl acetate with sodium hydroxide base is to be predicted.
Concept introduction:
In the claisen-ester condensation, nucleophilic acyl substitution takes place on an ester. The enolate ion acts as a nucleophile. It attacks the carbonyl carbon to form a tetrahedral intermediate. Acidity of beta-keto ester products is higher than simple ketones, aldehydes and esters.

Want to see the full answer?
Check out a sample textbook solution
Chapter 22 Solutions
Organic Chemistry, Books a la Carte Edition (9th Edition)
- How many chiral centers are there in the following molecule? HO 0 1 ○ 2 ♡ 4 'N'arrow_forwardThe following chemical structure represents a molecule of what molecular formula?arrow_forwardWhich region(s) of the following phospholipid is/are hydrophobic? RO I hydro-water phobic-dislikes = Hydrophobic dislikes water ○ I only Il only I and III only II and IV only O II, III, and IV only III || IVarrow_forward
- Chemistry: The Molecular ScienceChemistryISBN:9781285199047Author:John W. Moore, Conrad L. StanitskiPublisher:Cengage Learning
