EBK STATISTICS FOR BUSINESS AND ECONOMI
13th Edition
ISBN: 8220103633567
Author: Sincich
Publisher: PEARSON
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Textbook Question
Chapter 2.2, Problem 2.22ACB
Stability of compounds in new drugs. Testing the metabolic stability of compounds used in drugs is the cornerstone of new drug discovery. Two important values computed from the testing phase are the fraction of compound unbound to plasma ( fup) and the fraction of compound unbound to microsomes ( fumic). A key formula for assessing stability assumes that the fup/fumic ratio is 1. Pharmacologists at Pfizer Global Research and Development investigated this phenomenon and reported the results in ACS Medicinal Chemistry Letters (Vol. 1, 201 0). The fup/fumic ratio was determined for each of 416 drugs in the Pfizer database. An SPSS graph describing the fup/fumic ratios is shown below.
- a. What type of graph is displayed?
- b. What is the quantitative variable summarized in the graph?
- c. Determine the proportion of fup/fumic ratios that fall above 1.
- d. Determine the proportion of fup/fumic ratios that fall below .4.
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Chapter 2 Solutions
EBK STATISTICS FOR BUSINESS AND ECONOMI
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Refer...Ch. 2.7 - Prob. 2.120ACACh. 2.7 - Prob. 2.121ACACh. 2.8 - Construct a scatterplot for the data in the...Ch. 2.8 - Construct a scatterplot for the data in the...Ch. 2.8 - Prob. 2.124ACBCh. 2.8 - Prob. 2.125ACBCh. 2.8 - Lobster trap placement. Strategic placement of...Ch. 2.8 - Does elevation impact hitting performance in...Ch. 2.8 - Prob. 2.128ACBCh. 2.8 - Prob. 2.129ACBCh. 2.8 - Spreading rate of spilled liquid A contract...Ch. 2.8 - Performance ratings of government agencies. The...Ch. 2.8 - Most valuable NFL teams. Refer to the Forbes...Ch. 2.8 - Best-paid CEOs. Refer to Glassdoor Economic...Ch. 2.8 - Prob. 2.134ACACh. 2.10 - Museum management. Refer to the Museum Management...Ch. 2.10 - Volkswagen emissions scandal. Refer to the...Ch. 2.10 - BP oil leak. 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