Human Physiology: An Integrated Approach (7th Edition)
Human Physiology: An Integrated Approach (7th Edition)
7th Edition
ISBN: 9780321981226
Author: Dee Unglaub Silverthorn
Publisher: PEARSON
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Chapter 22, Problem 20CC
Summary Introduction

To describe: The potential side effects of increasing urinary glucose excretion.

Introduction: Diabetes mellitus is a metabolic disorder associated with the pancreatic endocrine system. It is characterized by an abnormally increased level of plasma glucose concentration that is hyperglycemia. This can be caused by deficient insulin secretion, abnormal target cell responsiveness, or both. The concentration or osmolarity of urine is a quantity of the water excreted by the kidneys. The kidney controls urine concentration by varying the amounts of water and Na+. They are reabsorbed in the distal nephron that is distal tubule and collecting duct.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

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Human Physiology: An Integrated Approach (7th Edition)

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