Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 22, Problem 1P

44322-22-1P

Summary Introduction

To examine: Whether the statement “In the small intestine, stem cells in the crypts divide asymmetrically to maintain the population of cells that make up the villi; after each division, one daughter remains a stem cell and the other begins to divide rapidly to produce differentiated progeny” is true or false.

Introduction:  Stem cells are the undifferentiated cells that can give rise to any type of cells in the body. These cells can either be embryonic stem cells or adult stem cells.

Expert Solution & Answer
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Answer to Problem 1P

Correct answer: The statement is true.

Explanation of Solution

An intestinal stem cell (ISC) has the ability to maintain itself throughout thelong periods of time (self-renewal) and give rise to mature cell types in order to maintain the integrity of the intestinal epithelium. The crypt of the small intestine is maintained by multipotent stem cells. They undergo asymmetric cell division to form a new stem cell and a committed daughter cell.

Hence, the statement is true.

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Molecular Biology of the Cell (Sixth Edition)

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