
Choose the best matching phrase in the right column for each of the terms in the left column.
a. isogenic lines | 1. Fraternal |
a. QTL | 2. blocks of association between variants at different loci |
a. response to selection | 3. proportion of total |
a. association mapping | 4. homozygous for all genomic regions |
a. MZ twins | 5. genes contributing to complex traits |
a. DZ twins | 6. Identical |
a. congenic lines | 7. measure of evolution |
a. linkage disequilibrium | 8. 0.5 for siblings |
a. heritability | 9. takes advantage of recombination over the course of a population’s history |
a. genetic relatedness | 10. contain introgressions |

a.
To determine:
The phrase that describes “isogenic lines” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction: An isogenic cell line can be defined as the cell line that is specifically engineered from the parental line through gene mutation.
Answer to Problem 1P
Correct answer:
isogenic lines: homozygous for all genomic regions
Explanation of Solution
Isogenic lines are in some manner related to the lines that are non-genetically modified and from which genetically modified strains are developed.

a.
To determine:
The phrase that describes “QTL” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction: QTL stands for quantitative trait loci and is a section of DNA which correlates with the specific variations of quantitative trait.
Answer to Problem 1P
Correct answer:
QTL: genes contributing to complex traits.
Explanation of Solution
QTL stands for Quantative Trait Loci. These are those segments of the DNA in which genes underlying a quantitative trait are considered. Hence, QTL relates to the genes that contribute towards different tratits.

a.
To determine:
The phrase that describes “response to selection” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction: Response to selection is associated with the type of advantages and the natural selection.
Answer to Problem 1P
Correct answer:
response to selection: measure of evolution
Explanation of Solution
Response to various types of selection taking place in a species or in a community is shown as the evolution of the species. It changes the heritable characters over many generations.

a.
To determine:
The phrase that describes “association mapping” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction: Mapping can be defined as the methods that are used for the identification of gene locus.
Answer to Problem 1P
Correct answer:
association mapping: takes advantage of recombination over the course of a population’s history.
Explanation of Solution
Mapping of loci contributing towards the quantitative trait is done by the method of association mapping. The process of association mapping takes advantage of linkage disequilibrium to link the phenotypes and the genotypes.

a.
To determine:
The phrase that describes “MZ twins” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
Monozygotic twins are those that are produced with the help of single zygote and possesses similar features.
Answer to Problem 1P
Correct answer:
MZ twins: identical
Explanation of Solution
An embryo developed by separation of a single zygote gives rise to monozygotic twins. These twins are identical to each other in all aspects, genetically as well as phenotypically.

a.
To determine:
The phrase that describes “DZ twins” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
Fertilization leads to the development of the zygote. When two different eggs and sperms are involved in the process, it results in the development of dizygotic twins.
Answer to Problem 1P
Correct answer:
DZ twins: fraternal
Explanation of Solution
Fertilization of two different eggs with the help of two different sperms gives rise to dizygotic twins. These twins are not identical to each other. Dizygotic embryos get implanted in the uterus at the same time. They are also known as fraternal twins.

a.
To determine:
The phrase that describes “congenic lines” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
The congenic types of strains are developed in the laboratory conditions by the process of mating of two different inbred strains.
Answer to Problem 1P
Correct answer:
congenic lines: contains introgressions
Explanation of Solution
Organisms having genetic difference only at a single locus relates to the congenic lines.

a.
To determine:
The phrase that describes “linkage disequilibrium” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
The process of linkage and equilibrium of alleles are associated with the process of disequilibrium.
Answer to Problem 1P
Correct answer:
linkage disequilibrium: blocks of association between variants at different loci
Explanation of Solution
Disequilibrium in the linkage and association of alleles at two or more loci are related to each other. It is the difference between the observed frequencies of a combination of two or more alleles that are present on different loci.

a.
To determine:
The phrase that describes “heritability” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
Heritability can be defined as the statistic unit in the field of genetics and breeding that helps in the estimation of degree of variation.
Answer to Problem 1P
Correct answer:
heritability: proportion of phenotypic variance attributed to genetic variance
Explanation of Solution
The proportion of the phenotypic variance that to the variation in the genotype is given by heritability.

a.
To determine:
The phrase that describes “genetic relatedness” among the options given below.
1. Fraternal |
2. blocks of association between variants at different loci |
3. proportion of total phenotypic variance attributed to genetic variance |
4. homozygous for all genomic regions |
5. genes contributing to complex traits |
6. Identical |
7. measure of evolution |
8. 0.5 for siblings |
9. takes advantage of recombination over the course of a population’s history |
10. contain introgressions |
Introduction:
Proportion or amount of genes can be estimated with the help of quantitative estimation that are shared among two persons.
Answer to Problem 1P
Correct answer:
genetic relatedness: 0.5 for siblings
Explanation of Solution
Quantitative estimation for the proportion of genes that are shared between two individuals is given by genetic relatedness. In a family, siblings from the same parents have a 0.5 genetic relatedness.
Want to see more full solutions like this?
Chapter 22 Solutions
Genetics: From Genes to Genomes
- Molecular Biology Please help and there is an attached image. Thank you. A bacteria has a gene whose protein/enzyme product is involved with the synthesis of a lipid necessary for the synthesis of the cell membrane. Expression of this gene requires the binding of a protein (called ACT) to a control sequence (called INC) next to the promoter. A. Is the expression/regulation of this gene an example of induction or repression?Please explain:B. Is this expression/regulation an example of positive or negative control?C. When the lipid is supplied in the media, the expression of the enzyme is turned off.Describe one likely mechanism for how this “turn off” is accomplished.arrow_forwardMolecular Biology Please help. Thank you. Discuss/define the following:(a) poly A polymerase (b) trans-splicing (c) operonarrow_forwardMolecular Biology Please help with question. Thank you in advance. Discuss, compare and contrast the structure of promoters inprokaryotes and eukaryotes.arrow_forward
- Molecular Biology Please help with question. Thank you You are studying the expression of the lac operon. You have isolated mutants as described below. In the absence of glucose, explain/describe what would happen, for each mutant, to the expression of the lac operon when you add lactose AND what would happen when the bacteria has used up all of the lactose (if the mutant is able to use lactose).1. Mutations in the lac repressor gene that would prevent the binding of lactose2. Mutations in the lac repressor gene that would prevent release of lactose once lactose hadbound3. Normally the lac repressor gene is located next to (a few hundred base pairs) and upstreamfrom the lac operon. Mutations in the lac repressor gene that move the lac repressor gene 100,000base pairs downstream.4. Mutations in the lac operator that would prevent binding of lac repressorarrow_forwardYou have returned to college to become a phylogeneticist. One of the first things you wish to do is determine how mammals, birds, and reptiles are related. Like any good scientist, you need to consider all available data objectively and without a preconceived “correct” answer. In pursuit of that, you should produce a phylogenetic tree based only on morphological features that show birds and mammals are more closely related. You will then produce a totally different tree, also using morphological features, that shows birds and reptiles are more closely related. Do not forget to include all three groups in both your trees. Based solely off the trees you produce, which relationship would you consider the more likely and why? Once you have answered that question, provide a brief summary of the “modern” understanding of the relationship between these three groups.arrow_forwardtrue or false, the reason geckos can walk on walls is hydrogen bonding between their foot pads and the moisture on the wall.arrow_forward
- Biology laboratory problem Please help. thank you You have 20 ul of DNA solution and 6X DNA loading buffer solution. You have to mix your DNA solution and DNA loading buffer before load DNA in an agarose gel. The concentration of the DNA loading buffer must be 1X in the DNA and DNA-loading buffer mixture after you mix them. For that, I will add _____ ul of 6X loading buffer to the 20 ul DNA solution.arrow_forwardBiology lab problem To make 20 ul of 5 mM MgCl2 solution using 50 mM MgCl2 stock solution and distilled water, I will mix ________ ul of 50 mM MgCl2 solution and ________ ul of distilled water. Please help . Thank youarrow_forwardBiology Please help. Thank you. Biology laboratory question You need 50 ml of 1% (w/v) agarose gel. Agarose is a powder. How would you make it? You can ignore the volume of agarose powder. Don't forget the unit.TBE buffer is used to make an agarose gel, not distilled water. I will add _______ of agarose powder into 50 ml of distilled water (final 50 ml).arrow_forward
- An urgent care center experienced the average patient admissions shown in the Table below during the weeks from the first week of December through the second week of April. Week Average Daily Admissions 1-Dec 11 2-Dec 14 3-Dec 17 4-Dec 15 1-Jan 12 2-Jan 11 3-Jan 9 4-Jan 9 1-Feb 12 2-Feb 8 3-Feb 13 4-Feb 11 1-Mar 15 2-Mar 17 3-Mar 14 4-Mar 19 5-Mar 13 1-Apr 17 2-Apr 13 Forecast admissions for the periods from the first week of December through the second week of April. Compare the forecast admissions to the actual admissions; What do you conclude?arrow_forwardAnalyze the effectiveness of the a drug treatment program based on the needs of 18-65 year olds who are in need of treatment by critically describing 4 things in the program is doing effectively and 4 things the program needs some improvement.arrow_forwardI have the first half finished... just need the bottom half.arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningConcepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax CollegeBiology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage Learning
- Biology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning



