The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes. Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Question

Want to see more full solutions like this?

Answer 1

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Students have asked these similar questions

Biochemistry Question. Please help solve. Thank you! Based upon knowledge of oxidation of bioorganic compounds and howmuch energy is released during their oxidation, rank the following, from most to least, with respect to how much energy would be produced from each during their oxidation. Explain your placement for each one.

Biochemistry Question.For the metabolism of amino acids what is the first step for theirbreakdown? Why is it necessary for this breakdown product to be transported to the liver? For the catabolism of the carbon backbone of these amino acids, there are 7 entry points into the “standard” metabolic pathways. List these 7 entry points and which amino acids are metabolized to these entry points. Please help. Thank you!

Biochemistry Question. Please help. Thank you. You are studying pyruvate utilization in mammals for ATP production under aerobic conditions and have synthesized pyruvate with Carbon #1 labelled with radioactive C14. After only one complete cycle of the TCA cycle, which of the TCA cycle intermediates would be labeled with C14? Explain your answer. Interestingly, you find C14 being excreted in the urine. How does it get there?

Answer 2

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Question

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 6

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 7

Chapter 22, Problem 1E

Summary Introduction

To explain: The advantages of having increased levels of GLUT1 and phosphofructokinase in muscles for the adaptation in high altitudes.

Concept introduction: GLUT 1 stands for glucose transporter 1, also called as solute carrier family 2. It was the first glucose transporter to be characterized. It helps in the transport of glucose across the plasma membrane of the mammalian cells. Phosphofructokinase is an enzyme that phosphorylates fructose 6-phosphate in the glycolysis.

Answer 8

Expert Solution & Answer

Explanation of Solution

The lower air pressure in the high altitudes makes it more difficult for oxygen to enter the vascular systems. Therefore, oxygen availability for the aerobic metabolism is low. In these conditions, the anaerobic pathway glycolysis will become more important in the active muscles. Glucose transporter 1 transports the glucose across the plasma membrane. The increase in GLUT 1 increases the intracellular glucose concentration. An increase in level of the enzyme phosphofructokinase increases the flux of glucose through the pathway.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Ch. 22 - Prob. 1E Ch. 22 - Prob. 2E Ch. 22 - 3. Toxins that occur in certain mushrooms block ?...Ch. 22 - Prob. 4E Ch. 22 - 5. The passive glucose transporter named GLUT1...Ch. 22 - Prob. 6E Ch. 22 - Prob. 7E Ch. 22 - 8. (a) Identify the two reactions that allow the...Ch. 22 - Prob. 9E Ch. 22 - Prob. 10E

Explanation of Solution

Want to see more full solutions like this?

Chapter 22 Solutions