Chapter 21.8, Problem 16P

Interpretation Introduction

(a)

Interpretation: The product that is formed by the reaction of the given compound with LDA in the presence of THF solution at low temperature, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be identified.

Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.

The bulky base like LDA always abstracts the proton from the side of less substituted $\text{C}-\text{atom}$.

Interpretation Introduction

(b)

Interpretation: The product that is formed by the reaction of the given compound with LDA in the presence of THF solution at low temperature, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be identified.

Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.

The bulky base like LDA always abstracts the proton from the side of less substituted $\text{C}-\text{atom}$.

Interpretation Introduction

(c)

Interpretation: The product that is formed by the reaction of the given compound with LDA in the presence of THF solution at low temperature, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be identified.

Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.

The bulky base like LDA always abstracts the proton from the side of less substituted $\text{C}-\text{atom}$.

Interpretation Introduction

(d)

Interpretation: The product that is formed by the reaction of the given compound with LDA in the presence of THF solution at low temperature, followed by ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}\text{I}$ is to be identified.

Concept introduction: The replacement or substitution of one functional group with another different functional group in any chemical reaction is termed as substitution reaction. The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.

The bulky base like LDA always abstracts the proton from the side of less substituted $\text{C}-\text{atom}$.