To describe how the given compound can be prepared using malonic ester synthesis Concept introduction: Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below, Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis) Steps involved in malonic ester synthesis are, Deprotonation of α carbon in malonic acid ester Alkylation of enolate Hydrolysis of ester using aqueous acid Decarboxylation at high temperature To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

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Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

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3) Propagation of uncertainty. Every measurement has uncertainty. In this problem, we'll evaluate the uncertainty in every step of a titration of potassium hydrogen phthalate (a common acid used in titrations, abbreviated KHP, formula CsH5KO4) with NaOH of an unknown concentration. The calculation that ultimately needs to be carried out is: concentration NaOH 1000 x mass KHP × purity KHP molar mass KHP x volume NaOH Measurements: a) You use a balance to weigh 0.3992 g of KHP. The uncertainty is ±0.15 mg (0.00015 g). b) You use a buret to slowly add NaOH to the KHP until it reaches the endpoint. It takes 18.73 mL of NaOH. The uncertainty of the burst is 0.03 mL.. c) The manufacturer states the purity of KHP is 100%±0.05%. d) Even though we don't think much about them, molar masses have uncertainty as well. The uncertainty comes from the distribution of isotopes, rather than random measurement error. The uncertainty in the elements composing KHP are: a. Carbon: b. Hydrogen: ±0.0008…

Don't used hand raiting and don't used Ai solution

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Expert Solution & Answer

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Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 6

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 7

Chapter 21.5, Problem 31PTS

(a)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 8

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 9

(b)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 10

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 11

(c)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 12

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 13

(d)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 14

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 15

(e)

Interpretation Introduction

Interpretation:

To describe how the given compound can be prepared using malonic ester synthesis

Concept introduction:

Malonic ester synthesis is a process in which an halide is converted to a carboxylic acid with two new carbon atoms (comes from malonic ester). By use of this method two new alkyl groups can be introduced. A general scheme of this synthesis is shown below,

Please do remember that if alkyldihalide is used for malonic ester synthesis a cyclic product is expected. (intramolecular malonic ester synthesis)

Steps involved in malonic ester synthesis are,

Deprotonation of α carbon in malonic acid ester

Alkylation of enolate

Hydrolysis of ester using aqueous acid

Decarboxylation at high temperature

To describe : To describe how the given compound can be synthesized using malonic ester synthesis.

Answer 16

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Answer 17

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Answer 18

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Answer 19

Ch. 21.1 - Prob. 1CC Ch. 21.1 - Prob. 2CC Ch. 21.1 - Prob. 3CC Ch. 21.1 - Prob. 1LTS Ch. 21.1 - Prob. 4PTS Ch. 21.1 - Prob. 5ATS Ch. 21.1 - Prob. 6CC Ch. 21.1 - Prob. 7CC Ch. 21.2 - Prob. 8CC Ch. 21.2 - Prob. 9CC

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