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Principles of Human Physiology (6th Edition)
6th Edition
ISBN: 9780134169804
Author: Cindy L. Stanfield
Publisher: PEARSON
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Chapter 21.5, Problem 21.3.3QC
Summary Introduction
To write:
Whether the mentioned processes such as gluconeogenesis, glycogenolysis and others are promoted by insulin or by glucagon.
Introduction:
Insulin is secreted by the beta cells of Islet of Langerhans of the pancreas which is a peptide chain. This is responsible for the absorption process and helps in production of energy-storing molecules or glucose.
Glucagon, on the other hand, is secreted by the Alpha cells of Islet of Langerhans of the pancreas which is also a peptide chain. This is most active after the absorption process and helps in the breakdown of glycogen whenever there is a need for extra energy or glucose in the body.
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Kinetics: One-Compartment First-Order Absorption
1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration.
Using this data and set of graphs, determine:(calculate for each variable)
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(b) k, ka, B1, and AUC* for the po data
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(d) relative bioavailability for po vs ip, Fpo/Fip
(e)absolute ip bioavailability, Fip
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Chapter 21 Solutions
Principles of Human Physiology (6th Edition)
Ch. 21.3 -
What are the storage forms of carbohydrates and...Ch. 21.3 - Prob. 21.1.2QCCh. 21.4 - Prob. 21.2.1QCCh. 21.4 - Prob. 21.2.2QCCh. 21.4 - Prob. 21.2.3QCCh. 21.5 - Prob. 21.3.1QCCh. 21.5 -
Sympathetic nervous activity and epinephrine...Ch. 21.5 -
For each of the following processes, indicate...Ch. 21.7 - Describe the roles of osteoblasts, osteoclasts,...Ch. 21.7 - Prob. 21.4.2QC
Ch. 21.9 - Prob. 21.5.1QCCh. 21.9 - Prob. 21.5.2QCCh. 21.9 - Prob. 21.5.3QCCh. 21.9 - Prob. 21.5.4QCCh. 21 - Prob. 1ECh. 21 - Prob. 2ECh. 21 - Prob. 3ECh. 21 - Prob. 4ECh. 21 - Prob. 5ECh. 21 - Prob. 6ECh. 21 -
Which of the following cell types is directly...Ch. 21 -
Which of the following is true of adulthood?...Ch. 21 -
Which form of thyroid hormone has greater...Ch. 21 - Prob. 10ECh. 21 - Prob. 11ECh. 21 - Prob. 12ECh. 21 - Prob. 13ECh. 21 - Prob. 14ECh. 21 - Prob. 15ECh. 21 - Prob. 16ECh. 21 - Prob. 17ECh. 21 - Prob. 18ECh. 21 - Prob. 19ECh. 21 -
Many of growth hormone's effects on target...Ch. 21 -
Closure of the epiphyseal plates is promoted by...Ch. 21 - Prob. 22ECh. 21 - Prob. 23ECh. 21 - Prob. 24ECh. 21 - Prob. 25ECh. 21 -
Describe the regulation of plasma glucose by...Ch. 21 -
Describe how insulin, glucagon, and the...Ch. 21 -
Describe the various factors that determine the...Ch. 21 -
Describe the similarities between the metabolic...Ch. 21 -
Describe the metabolic actions of growth hormone,...Ch. 21 -
Some athletes have used anabolic steroids in...Ch. 21 -
Many hormone deficiencies are genetic in origin....Ch. 21 -
Physicians often recommend that people with...Ch. 21 -
An obese patient goes to his doctor complaining...
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