Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 21.5, Problem 13AYP
Summary Introduction
To list:
The possible causative agents for each of the diseases affecting the lower respiratory tract, tuberculosis, community-acquired pneumonia, healthcare-associated pneumonia, and Hantavirus pulmonary syndrome.
Concept introduction:
Diseases are caused due to infection by various microorganisms like strains of bacteria and viruses. The respiratory system is affected leading to the destruction of the lining of the epithelial layer of lungs.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 21 Solutions
Microbiology: A Systems Approach
Ch. 21.1 - Prob. 1AYPCh. 21.1 - Prob. 2AYPCh. 21.2 - Prob. 3AYPCh. 21.3 - Prob. 4AYPCh. 21.3 - Prob. 5AYPCh. 21.3 - Prob. 6AYPCh. 21.4 - Prob. 7AYPCh. 21.4 - Prob. 8AYPCh. 21.4 - Prob. 9AYPCh. 21.4 - Prob. 10AYP
Ch. 21.4 - Plan a response for a situation in which a patient...Ch. 21.4 - Compare and contrast antigenic drift and antigenic...Ch. 21.5 - Prob. 13AYPCh. 21.5 - Prob. 14AYPCh. 21.5 - Prob. 15AYPCh. 21.5 - Prob. 16AYPCh. 21.5 - Prob. 17AYPCh. 21.5 - Prob. 18AYPCh. 21.5 - Prob. 19AYPCh. 21 - Prob. 1MCQCh. 21 - Prob. 2MCQCh. 21 - Which is not a characteristic of Streptococcus...Ch. 21 - The common stain used to identify Mycobacterium...Ch. 21 - Prob. 5MCQCh. 21 - Prob. 6MCQCh. 21 - Which of the following infections often has a...Ch. 21 - Prob. 8MCQCh. 21 - Prob. 9MCQCh. 21 - Prob. 10MCQCh. 21 - Prob. 11TFCh. 21 - Prob. 12TFCh. 21 - Prob. 13TFCh. 21 - Prob. 14TFCh. 21 - Prob. 15TFCh. 21 - Prob. 1CTQCh. 21 - Prob. 2CTQCh. 21 - Prob. 3CTQCh. 21 - In an episode of the television show House. Dr....Ch. 21 - Prob. 5CTQCh. 21 - Prob. 1VCCh. 21 - Prob. 1CM
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