EP ESSENTIAL ORG.CHEM.-MOD.MASTERING
EP ESSENTIAL ORG.CHEM.-MOD.MASTERING
3rd Edition
ISBN: 9780133858501
Author: Bruice
Publisher: PEARSON CO
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Chapter 21.4, Problem 3P

The 2’,3’-cyclic phosphodiester that is formed (Figure 21.7) when RNA is cleaved reacts with water, forming a mixture of nucleotide 2’- and 3’-phosphates. Propose a mechanism for this reaction.

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Draw the DNA dinucleotide (two nucleotides joined by a phosphodiester) formed if two deoxythymidine monophosphates undergo a condensation reaction. Label the 5’ and 3’ ends of your structure. Identify the phosphodiester bond.
There are two families of nitrogenous bases. The pyrimidines have one six-membered ring carbon and nitrogen atoms while purines are larger with a six-membered ring fused to a five -membered ring. Identify the type of nitrogenous base from monomer nucleotides. How can you tell?
What is the structure, origin and catalytic role of Nicotinamide nucleotides?

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Nucleic acids - DNA and RNA structure; Author: MEDSimplified;https://www.youtube.com/watch?v=0lZRAShqft0;License: Standard YouTube License, CC-BY