Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+)
Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+)
3rd Edition
ISBN: 9780137533268
Author: Paula Bruice
Publisher: PEARSON+
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Chapter 21, Problem 33P
Interpretation Introduction

Interpretation:

5-Bromouracil causes mutations in DNA.  Reason for this should be determined.

Concept introduction:

A parent DNA molecule consists of two poly nucleotide chains held together by bonds between complementary nitrogen bases.

A base is nitrogen containing heterocyclic compound which is found in DNA and RNA.

There are mainly five nitrogen bases.

  1. (1) Adenine
  2. (2) Guanine
  3. (3) Cytosine
  4. (4) Thymine
  5. (5) Uracil

In DNA Adenine always makes a double bond with Thymine (A=T) and cytosine always makes triple bond with guanine (GC)

Enol is a tautomer which exhibiting a special type of functional isomerism namely tautomerism.

Tautomerism is a special type of functional isomerism in which isomers are in dynamic equilibrium with each other.

Mutation is the process that results in change in the sequence of the DNA, and the compound which causes mutation is known as mutagenic compound.

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Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+)

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