Chapter 21, Problem 32CQ

(a)

Summary Introduction

To write: An equation for the urea hydrolysis by urease.

Concept introduction:

Helicobacter pylori are a group of gram-negative bacteria that causes infection in stomach. It can cause peptic and gastric ulcers. H.pylori produces a nickel-containing urease that catalyzes the urea hydrolysis to produce ammonia and carbonic acid.

(b)

Summary Introduction

To explain: The reason why the given reaction could help establish a more hospitable environment for H. pylori, which tolerates acid but prefers to grow at near-neutral pH.

Concept introduction:

Helicobacter pylori is a group of gram-negative bacteria that causes infection in stomach. It can cause peptic and gastric ulcers. H.pylori produces a nickel-containing urease that catalyzes the urea hydrolysis to produce ammonia and carbonic acid.