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Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 21, Problem 30CQ
Summary Introduction
To explain: The apparent paradox related to the enzymatic activity of urea cycle.
Concept introduction:
The urea cycle involves the production of urea through many biochemical reactions. The urea cycle involves the conversion of excess nitrogen generated from the amino acid breakdown in the proteins into an excretable form called urea. This process mainly involves five enzymes in the urea cycle. They are ornithine transcarbamylase (OTC), carbamoyl-phosphate synthetase 1 (CPS1), arginase 1 (ARG1), argininosuccinate synthetase (ASS1), and argininosuccinate lyase (ASL). In the presence of the enzyme, the nitrogen can be converted into urea.
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Chapter 21 Solutions
Fundamentals of Biochemistry: Life at the Molecular Level
Ch. 21 - Prob. 1ECh. 21 - 2. The compound shown below inhibits an...Ch. 21 - Prob. 3ECh. 21 - Prob. 4ECh. 21 - 5. Explain why it was advantageous for human...Ch. 21 - Prob. 6ECh. 21 - 7. Which of the 20 “standard” amino acids are (a)...Ch. 21 - 8. Alanine, cysteine, glycine, serine, and...Ch. 21 - Prob. 9ECh. 21 - 10. Draw the amino acid-Schiff base that forms in...
Ch. 21 - Prob. 11ECh. 21 - Prob. 12ECh. 21 - 13. Which three mammalian enzymes can potentially...Ch. 21 - Prob. 14ECh. 21 - Prob. 15ECh. 21 - Prob. 16ECh. 21 - Prob. 17ECh. 21 - Prob. 18ECh. 21 - Prob. 19ECh. 21 - 20. From what amino acid is the signaling molecule...Ch. 21 - Prob. 21ECh. 21 - Prob. 22ECh. 21 - 23. Describe the reactions that convert...Ch. 21 - Prob. 24ECh. 21 - 25. One of the symptoms of kwashiorkor, the...Ch. 21 - 26. From what amino acid is melatonin derived?...Ch. 21 - Prob. 27ECh. 21 - 28. Nitrosomonas is a photophobic (light-avoiding)...Ch. 21 - Prob. 29CQCh. 21 - Prob. 30CQCh. 21 - 31. (a) How many ATP equivalents are consumed by...Ch. 21 - Prob. 32CQCh. 21 - Prob. 33CQCh. 21 - Prob. 34CQCh. 21 - Prob. 35CQCh. 21 - Prob. 36CQCh. 21 - 37. The nucleotide deoxyuridylate (dUMP) is...Ch. 21 - 38. Proliferating cells require NADPH for...Ch. 21 - 39. Mouse embryonic stem cells produce high levels...Ch. 21 - 40. Rice plants that have been engineered to...Ch. 21 - Prob. 41CQCh. 21 - Prob. 1MTE
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- Problem 15 of 15 Submit Using the following reaction data points, construct Lineweaver-Burk plots for an enzyme with and without an inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Using the information from this plot, determine the type of inhibitor present. 1 mM-1 1 s mM -1 [S]' V' with 10 μg per 20 54 10 36 20 5 27 2.5 23 1.25 20 Answer: |||arrow_forward12:33 CO Problem 4 of 15 4G 54% Done On the following Lineweaver-Burk -1 plot, identify the by dragging the Km point to the appropriate value. 1/V 40 35- 30- 25 20 15 10- T Км -15 10 -5 0 5 ||| 10 15 №20 25 25 30 1/[S] Г powered by desmosarrow_forward1:30 5G 47% Problem 10 of 15 Submit Using the following reaction data points, construct a Lineweaver-Burk plot for an enzyme with and without a competitive inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. 1 -1 1 mM [S]' s mM¹ with 10 mg pe 20 V' 54 10 36 > ст 5 27 2.5 23 1.25 20 Answer: |||arrow_forward
- Problem 14 of 15 Submit Using the following reaction data points, construct Lineweaver-Burk plots for an enzyme with and without an inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Using the information from this plot, determine the type of inhibitor present. 1 mM-1 1 s mM -1 [S]' V' with 10 μg per 20 54 10 36 20 5 27 2.5 23 1.25 20 Answer: |||arrow_forward12:36 CO Problem 9 of 15 4G. 53% Submit Using the following reaction data points, construct a Lineweaver-Burk plot by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Based on the plot, determine the value of the catalytic efficiency (specificity constant) given that the enzyme concentration in this experiment is 5.0 μ.Μ. 1 [S] ¨‚ μM-1 1 V sμM-1 100.0 0.100 75.0 0.080 50.0 0.060 15.0 0.030 10.0 0.025 5.0 0.020 Answer: ||| O Гarrow_forwardProblem 11 of 15 Submit Using the following reaction data points, construct a Lineweaver-Burk plot for an enzyme with and without a noncompetitive inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. 1 -1 1 mM [S]' 20 V' s mM¹ with 10 μg per 54 10 36 > ст 5 27 2.5 23 1.25 20 Answer: |||arrow_forward
- Problem 13 of 15 Submit Using the following reaction data points, construct Lineweaver-Burk plots for an enzyme with and without an inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Using the information from this plot, determine the type of inhibitor present. 1 mM-1 1 s mM -1 [S]' V' with 10 μg per 20 54 10 36 20 5 27 2.5 23 1.25 20 Answer: |||arrow_forward12:33 CO Problem 8 of 15 4G. 53% Submit Using the following reaction data points, construct a Lineweaver-Burk plot by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. Based on the plot, determine the value of kcat given that the enzyme concentration in this experiment is 5.0 μM. 1 [S] , мм -1 1 V₁ s μM 1 100.0 0.100 75.0 0.080 50.0 0.060 15.0 0.030 10.0 0.025 5.0 0.020 Answer: ||| Гarrow_forward1:33 5G. 46% Problem 12 of 15 Submit Using the following reaction data points, construct a Lineweaver-Burk plot for an enzyme with and without an uncompetitive inhibitor by dragging the points to their relevant coordinates on the graph and drawing a line of best fit. 1 -1 1 mM [S]' 20 V' s mM¹ with 10 μg per 54 10 36 > ст 5 27 2.5 23 1.25 20 Answer: |||arrow_forward
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