GENETIC ANALYSIS: AN INTEG. APP. W/MAS
2nd Edition
ISBN: 9781323142790
Author: Sanders
Publisher: Pearson Custom Publishing
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Chapter 21, Problem 23P
In human gestational development, abnormalities of the closure of the lower part of the midface can result in cleft lip, if the lip alone is affected by the closure defect, or in cleft lip and palate (the roof of the mouth), if the closure defect is more extensive. Cleft lip and cleft lip with cleft palate are multifactorial disorders that are threshold traits. A family with a history of either condition has a significantly increased chance of a recurrence of midface cleft disorder in comparison with families without such a history. However, the recurrence risk of a midface cleft disorder is higher in families with a history of cleft lip with cleft palate than in families with a history of cleft lip alone.
a. Suppose a friend of yours who has not taken genetics asks you to explain these observations. Construct a genetic explanation for the increased recurrence risk of midface clefting in families that have a history of cleft disorders versus families without a history of such disorders.
b. Construct a similar explanation of why the recurrence risk of a cleft disorder is higher in families with a history of cleft lip with cleft palate than in families with a history of cleft lip alone.
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Chapter 21 Solutions
GENETIC ANALYSIS: AN INTEG. APP. W/MAS
Ch. 21 - Which of the following traits would you expect to...Ch. 21 - 19.2 For the traits listed in the previous...Ch. 21 - Compare and contrast broad sense heritability and...Ch. 21 - 19.4 In a cross of two pure-breeding lines of...Ch. 21 - 19.5 Describe the difference between continuous...Ch. 21 - Prob. 6PCh. 21 - 19.7 Provide a definition and an example for each...Ch. 21 - 19.10 Three pairs of genes with two alleles each (...Ch. 21 - Prob. 9PCh. 21 - 19.12 Two inbred lines of sunflowers produce...
Ch. 21 - Prob. 11PCh. 21 - 19.14 In Nicotiana, two inbred strains produce...Ch. 21 - 19.15 Suppose the length of maize ears has narrow...Ch. 21 - In a line of cherry tomatoes, the average fruit...Ch. 21 - 19.17 Two purebreeding wheat strains, one...Ch. 21 - Prob. 16PCh. 21 - During a visit with your grandparents, they...Ch. 21 - 19.20 An association of racehorse owners is...Ch. 21 - Prob. 19PCh. 21 - Suppose a polygenic system for producing color in...Ch. 21 - New Zealand lamb breeders measure the following...Ch. 21 - Cattle breeders would like to improve the protein...Ch. 21 - In human gestational development, abnormalities of...Ch. 21 - The children of couples in which one partner has...Ch. 21 - Answer the following in regard to multifactorial...
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