Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
12th Edition
ISBN: 9780134811390
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 21, Problem 21ESP
Researchers have compared candidate loci in humans and rats in search of loci in the human genome that are likely to contribute to the constellation of factors leading to hypertension [Stoll, M., et al. (2000). Genome Res. 10:473–482]. Through this research, they identified 26 chromosomal regions that they consider likely to contain hypertension genes. How can comparative genomics aid in the identification of genes responsible for such a complex human disease? The researchers state that comparisons of rat and human candidate loci to those in the mouse may help validate their studies. Why might this be so?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Luke recently moved to a new apartment and wants to grow houseplants but isn't sure which room will be the best fit for them. Apply your knowledge of the scientific method to recommend a strategy for Luke to follow when determining the ideal location for houseplants in his new apartment.
A farmer has noticed that his soybean plants produce more beans in some years than others. He claims to always apply the same amount of fertilizer to the plants, but he suspects the difference in crop yield may have something to do with the amount of water the crops receive. The farmer has observed that the soybeans on his farm usually receive between 0 to 0.5 inches of water per day, but he is unsure of the optimal average daily amount of water with which to irrigate.
1. State a question that addresses the farmer’s problem
2. Conduct online research on “soybean crop irrigation" and record a brief summary of the findings
3. Construct a testable hypothesis and record i
4. Design an experiment to test the hypothesis and describe the procedures, variables, and data to be collected
5. What is the purpose of a control group in an experiment? What would the control groups be for each of your designed experiments in this exercise?
6. Describe the data that would be recorded in each of the…
A farmer has noticed that his soybean plants produce more beans in some years than others. He claims to always apply the same amount of fertilizer to the plants, but he suspects the difference in crop yield may have something to do with the amount of water the crops receive. The farmer has observed that the soybeans on his farm usually receive between 0 to 0.5 inches of water per day, but he is unsure of the optimal average daily amount of water with which to irrigate.
1. State a question that addresses the farmer’s problem
2. Conduct online research on “soybean crop irrigation" and record a brief summary of the findings
3. Construct a testable hypothesis and record i
4. Design an experiment to test the hypothesis and describe the procedures, variables, and data to be collected
Chapter 21 Solutions
Concepts of Genetics Plus Mastering Genetics with Pearson eText -- Access Card Package (12th Edition) (What's New in Genetics)
Ch. 21 - In a sequence encompassing 99.4 percent of the...Ch. 21 - Annotation of a proteome attempts to relate each...Ch. 21 - Because of its accessibility and biological...Ch. 21 - If you had Crohns disease or ulcerative colitis...Ch. 21 - Prob. 2CSCh. 21 - Prob. 3CSCh. 21 - HOW DO WE KNOW? In this chapter, we focused on the...Ch. 21 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 21 - What is functional genomics? How does it differ...Ch. 21 - Compare and contrast WGS to a map-based cloning...
Ch. 21 - What is bioinformatics, and why is this discipline...Ch. 21 - Annotation involves identifying genes and...Ch. 21 - Prob. 7PDQCh. 21 - BLAST searches and related applications are...Ch. 21 - What functional information about a genome can be...Ch. 21 - Describe three major goals of the Human Genome...Ch. 21 - Describe the human genome in terms of genome size,...Ch. 21 - The Human Genome Project has demonstrated that in...Ch. 21 - Through the Human Genome Project (HGP), a...Ch. 21 - Explain differences between whole-genome...Ch. 21 - Describe the significance of the Genome 10K...Ch. 21 - Prob. 16PDQCh. 21 - Prob. 17PDQCh. 21 - What are DNA microarrays? How are they used?Ch. 21 - Prob. 19PDQCh. 21 - Prob. 20PDQCh. 21 - Researchers have compared candidate loci in humans...Ch. 21 - Homology can be defined as the presence of common...Ch. 21 - Prob. 23ESPCh. 21 - Prob. 24ESPCh. 21 - Whole-exome sequencing (WES) is helping physicians...Ch. 21 - Recall that when the HGP was completed, more than...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- A pharmaceutical company has developed a new weight loss drug for adults. Preliminary tests show that the drug seems to be fairly effective in about 75% of test subjects. The drug company thinks that the drug might be most effective in overweight individuals, but they are unsure to whom they should market the product. Use the scientific method to address the pharmaceutical company’s needs: State a research question that addresses the pharmaceutical company's problem Conduct online research on “Body Mass Index” categories and record a brief summary Construct a testable hypothesis and record in Design an experiment to test the hypothesis and describe the procedures, variables, and data to be collected What is the purpose of a control group in an experiment? What would the control groups be for each of your designed experiments in this exercise? Describe the data that would be recorded in each of the experiments you designed. Would it be classified as quantitative or…arrow_forwardPatients with multiple sclerosis frequently suffer from blurred vision. Drug X was developed to reduce blurred vision in healthy patients, but the effectiveness had not been tested on those suffering from multiple sclerosis. A study was conducted to determine if Drug X is effective at reducing blurry vision in multiple sclerosis patients. To be considered effective, a drug must reduce blurred vision by more than 30% in patients. Researchers predicted that a 20 mg dose of the drug would be effective for treating blurred vision in multiple sclerosis patients by reducing blurred vision by more than 30%. Drug X was administered to groups of multiple sclerosis patients at three doses (10 mg/day, 20 mg/day, 30 mg/day) for three weeks. A fourth group of patients was given a placebo containing no drug X for the same length of time. Vision clarity was measured for each patient before and after the three-week period using a standard vision test. The results were analyzed and graphed (See Figure…arrow_forwardSvp je voulais demander l aide pour mon exercicearrow_forward
- Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?arrow_forwardRespond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.arrow_forwardanswer questions 1-10arrow_forward
- Answer Question 1-9arrow_forwardEx: Mr. Mandarich wanted to see if the color of light shined on a planthad an effect on the number of leaves it had. He gathered a group ofthe same species of plants, gave them the same amount of water, anddid the test for the same amount of time. Only the color of light waschanged. IV:DV:Constants:Control Gr:arrow_forwardethical considerations in medical imagingarrow_forward
- Please correct answer and don't used hand raiting and don't used Ai solutionarrow_forward2. In one of the reactions of the citric acid cycle, malate is oxidized to oxaloacetate. When this reaction is considered in isolation, a small amount of malate remains and is not oxidized. The best term to explain this is a. enthalpy b. entropy c. equilibrium d. free energy e. loss of energyarrow_forward18. The citric acid cycle takes place in a. the chloroplasts b. the cytosol c. the inner mitochondrial membrane d. between the two mitochondrial membranes e. the mitochondrial matrix 40 WILarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax College
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)BiologyISBN:9781305389892Author:Peter J. Russell, Paul E. Hertz, Beverly McMillanPublisher:Cengage Learning
Case Studies In Health Information ManagementBiologyISBN:9781337676908Author:SCHNERINGPublisher:Cengage
Biology (MindTap Course List)BiologyISBN:9781337392938Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. BergPublisher:Cengage LearningEssentials Health Info Management Principles/Prac...Health & NutritionISBN:9780357191651Author:BowiePublisher:Cengage
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Case Studies In Health Information Management
Biology
ISBN:9781337676908
Author:SCHNERING
Publisher:Cengage
Biology (MindTap Course List)
Biology
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Cengage Learning
Essentials Health Info Management Principles/Prac...
Health & Nutrition
ISBN:9780357191651
Author:Bowie
Publisher:Cengage
QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY