Chapter 21, Problem 19P

Interpretation Introduction

Interpretation:

The statement “entropy for ring closure in ring closing metathesis is not large for most systems” is to be explained.

Concept introduction:

Ring closing metathesis is a process in organic chemistry by which various unsaturated rings are synthesized by intramolecular metathesis of terminal alkenes.

These reactions are catalyzed by metal complexes. Grubbs II reagent is a ruthenium-based carbene complex used as a catalyst in ring closing metathesis. These catalysts can form di-substituted or tri-substituted alkenes.

The thermodynamic and kinetic control of reaction depends on exact conditions of the reaction, substrate, and catalyst.

The entropy for ring closure in ring closing metathesis is not large as these reactions have enthalpy favorability.