Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 20.5, Problem 1R
Summary Introduction
To review:
A hypothesis to explain that a deleterious allele, like sickle-cell anemia, could become fixed in a population.
Introduction:
Sickle-cell anemia is a genetic disease, which occurs in individuals, who are homozygous recessive for an allele that affects the hemoglobin gene. There is a strong negative selection against this allele, but it is quite common in central Africa, particularly in areas where malaria was highly prevalent historically.
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Life: The Science of Biology
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