Genetics: A Conceptual Approach
Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319127121
Author: Pierce
Publisher: MAC HIGHER
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Chapter 20.2, Problem 10COQ
Summary Introduction

To explain:

What are homologous sequences.

Introduction:

Phylogenetic evolutionary history consists of the analysis of the sequences of the common ancestors and the formation of new species by diversification and divergence of the original species.

Summary Introduction

To explain:

What is the difference between orthologs and paralogs.

Introduction:

Orthologs are those sequences that have evolved from sequences from a common ancestor in the evolutionary history but are present in different organisms. Paralogs are those sequences which have evolved due to the process of gene duplication in the genome.

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*Example 2: Tracing the path of an autosomal dominant trait Trait: Neurofibromatosis Forms of the trait: The dominant form is neurofibromatosis, caused by the production of an abnormal form of the protein neurofibromin. Affected individuals show spots of abnormal skin pigmentation and non-cancerous tumors that can interfere with the nervous system and cause blindness. Some tumors can convert to a cancerous form. i The recessive form is a normal protein - in other words, no neurofibromatosis.moovi A typical pedigree for a family that carries neurofibromatosis is shown below. Note that carriers are not indicated with half-colored shapes in this chart. Use the letter "N" to indicate the dominant neurofibromatosis allele, and the letter "n" for the normal allele. Nn nn nn 2 nn Nn A 3 N-
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