Organic Chemistry (9th Edition)
Organic Chemistry (9th Edition)
9th Edition
ISBN: 9780321971371
Author: Leroy G. Wade, Jan W. Simek
Publisher: PEARSON
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Chapter 20.12, Problem 20.18P

Show how to synthesize the following compounds, using appropriate carboxylic acids and amines.

Chapter 20.12, Problem 20.18P, Show how to synthesize the following compounds, using appropriate carboxylic acids and amines.

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All of these compounds would be produced (I think).  In my book, I don't see any rules about yield in this case, like explaining that one product would be present in less yield for this reason or that reason.  Please explain why some of these produce less yield than others.
5. Fill in the missing molecules in the following reaction pathway. TMSO Heat + CI then HF O₂N (1.0 equiv) AICI 3 OMe
e. O₂N NO2 1. excess H2, Pd/C 2. excess NaNO2, HCI 3. excess CuCN

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Organic Chemistry (9th Edition)

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How to Design a Total Synthesis; Author: Chemistry Unleashed;https://www.youtube.com/watch?v=9jRfAJJO7mM;License: Standard YouTube License, CC-BY