Chapter 20, Problem 5CTQ

(a)

Summary Introduction

To discuss:

Whether or not genetics play role in HIV infection.

Concept introduction:

The human immunodeficiency virus is a lentivirus which is a causative agent of AIDS. This virus attacks T-cells, that provide immunity against the infection. The decline in a number of T cells results in loss of the immunity and individual becomes susceptible to the virus. HIV enzyme, reverse transcriptase transcribes the viral genetic material RNA to DNA that can actively incorporate itself into the genetic material of the host causing AIDS.

(b)

Summary Introduction

To provide:

Evidence in support of or refuting the following statement: An HIV-positive individual will always harbor the virus even if no viral load is detectable by PCR or other methods.

Concept introduction:

HIV (Human Immuno Virus) is a virus that can residue in the human cells without expressing its effect. It belongs to the retroviruses family and contains single-stranded RNA. HIV enzyme “reverse transcriptase” transcribes its viral genetic material, RNA into DNA so that it can actively incorporate itself into the genetic material (DNA) of the host.