The reason for cell attachment differences to their extracellular matrices. Introduction : Every cell attaches to its extracellular matrix through some connections and there are two types of junction that connect the cells and its matrix whose attachment dependents are on the presence of integrin proteins. Such integrin dependent connections are called as via focal adhesion (or focal contact sites) and the other one is called as hemi-desmosomes. The occurrence of these types of connections in cell is reliant on the nature of cell. The focal adhesions will be present in the cells that need the mechanical signaling and need to move over the cell surfaces(for example, Fibroblast cells).Whereas, the Hemi-desmosomes occur in such cells which does not require swarming and mostly will be fixed in a particular area(for example, epithelial cells).

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Chapter 20, Problem 4Q

Summary Introduction

To explain: The reason for cell attachment differences to their extracellular matrices.

Introduction: Every cell attaches to its extracellular matrix through some connections and there are two types of junction that connect the cells and its matrix whose attachment dependents are on the presence of integrin proteins. Such integrin dependent connections are called as via focal adhesion (or focal contact sites) and the other one is called as hemi-desmosomes. The occurrence of these types of connections in cell is reliant on the nature of cell. The focal adhesions will be present in the cells that need the mechanical signaling and need to move over the cell surfaces(for example, Fibroblast cells).Whereas, the Hemi-desmosomes occur in such cells which does not require swarming and mostly will be fixed in a particular area(for example, epithelial cells).

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